AC-LEHD-AFC Chemical Properties

Boiling point:

1211.9±65.0 °C(Predicted)

Density 

1.457±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

DMSO/DMF: 20 mM

form 

powder

pka

4.07±0.10(Predicted)

color 

white

Water Solubility 

Soluble to 1 mg/ml in water

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

AC-LEHD-AFC Usage And Synthesis

Uses

Ac-LEHD-AFC Trifluoroacetic Acid Salt is a fluorogenic substrate that is cleaved by caspases (4,5 and 9). This activity is quantified by fluorescent detection of free AFC. Caspase-9 activation is critical for intrinsic cell death.

Biological Activity

Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.

AC-LEHD-AFC(210345-03-2)Related Product Information

• Z-PHE-DL-ALA-FLUOROMETHYLKETONE
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• AC-VEID-AMC
• Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE
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• AC-VDVAD-CHO
• AC-DEVD-AFC
• PAC1
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• AC-LEU-GLU-THR-ASP-AFC
• AC-VDVAD-PNA
• Z-VAD-FMK
• AC-LEU-GLU-HIS-ASP-AMC
• AC-LEHD-AFC