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N-Succinimidyl S-Acetylthioglycolate

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N-Succinimidyl S-Acetylthioglycolate Basic information

Product Name:
N-Succinimidyl S-Acetylthioglycolate
Synonyms:
  • n-hydroxysuccinimides-acetylthioacetate
  • SUCCINIMIDYL ACETYLTHIOACETATE
  • SATA
  • S-ACETYLTHIOGLYCOLIC ACID NHS ESTER
  • S-ACETYLTHIOGLYCOLIC ACID N-HYDROXYSUCCINIMIDE ESTER
  • S-ACETYLTHIOGLYCOLIC ACID N-SUCCINIMIDYL ESTER
  • S-ACETYLTHIOACETIC ACID-N-HYDROXYSUCCINIMIDE ESTER
  • N-SUCCINIMIDYL (ACETYLTHIO)ACETATE
CAS:
76931-93-6
MF:
C8H9NO5S
MW:
231.23
EINECS:
678-479-6
Product Categories:
  • MTS & Sulfhydryl Active Reagents
  • Building Blocks
  • Chemical Biology
  • Chemical Synthesis
  • Crosslinkers
  • Crosslinking
  • Heterobifunctional Cross-Linking Reagents
  • Linkers and Crosslinkers
  • Organic Building Blocks
  • Protected Thiols/Mercaptans
  • Protein Modification
  • Protein Structural Analysis
  • Proteomics
  • Sulfur Compounds
  • MTS and Sulfhydryl Active Reagents
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Succinimides
  • Heterocycles
  • Protein Modification Reagents
  • proteinmod
Mol File:
76931-93-6.mol
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N-Succinimidyl S-Acetylthioglycolate Chemical Properties

Melting point:
84-89 °C
Boiling point:
337.3±44.0 °C(Predicted)
Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
acetonitrile: 50 mg/mL
form 
powder
color 
White to Off-White
BRN 
7815491
Stability:
Moisture Sensitive
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Safety Information

Safety Statements 
25/26
WGK Germany 
3
3-10-23
HS Code 
29309090

MSDS

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N-Succinimidyl S-Acetylthioglycolate Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Uses

N-Succinimidyl S-Acetylthioglycolate can be used as Thiolating reagent for primary amines; thiol can be deprotected under mild conditions and be useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Uses

Reacts with primary amines to add protected sulfhydryls.

N-Succinimidyl S-AcetylthioglycolateSupplier

Chongqing Xingcan Pharmaceutical Technology Co., Ltd. Gold
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