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PINOCEMBRIN

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PINOCEMBRIN Basic information

Product Name:
PINOCEMBRIN
Synonyms:
  • PINOCEMBRIN
  • 5,7-DIHYDROXY-2-PHENYL-CHROMAN-4-ONE
  • 5,7-DIHYDROXY-3'4'5'-FLAVANONE
  • 5,7-DIHYDROXYFLAVANONE
  • 2-Phenyl-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one
  • 5,7-Dihydroxy-2,3-dihydro-2-phenyl-4H-1-benzopyran-4-one
  • 5,7-Dihydroxy-2-phenyl-4-chromanone
  • 5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
CAS:
68745-38-0
MF:
C15H12O4
MW:
256.25
Product Categories:
  • PER - POLAApplication Index
  • Cell Signaling Enzymes
  • Chemical Structure
  • Drugs&Metabolites
  • Forensic and Veterinary Standards
  • Neat CompoundsDrugs of Abuse
  • OthersAlphabetic
  • P
  • Signal Transduction
Mol File:
68745-38-0.mol
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PINOCEMBRIN Chemical Properties

Melting point:
202-203°C
Boiling point:
511.1±50.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly, heated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
7.50±0.40(Predicted)
color 
White to Pale Beige
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PINOCEMBRIN Usage And Synthesis

Uses

Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.

PINOCEMBRINSupplier

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