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Carboprost

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Carboprost Basic information

Product Name:
Carboprost
Synonyms:
  • (5z,9-alpha,11-alpha,13e,15s)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1
  • Carboprost Trometamol Impurity B (Carboprost)
  • 15-methylpgf2-alpha
  • 15s)-13e
  • methyl-pgf2-alpha
  • -oicacid
  • prosta-5,13-dien-1-oicacid,9,11,15-trihydroxy-15-methyl-,(5z,9-alpha,11-alph
  • prostin15m
CAS:
35700-23-3
MF:
C21H36O5
MW:
368.51
Product Categories:
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
35700-23-3.mol
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Carboprost Chemical Properties

Melting point:
79-82°C
Boiling point:
418.83°C (rough estimate)
Density 
1.0390 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
form 
Solid
pka
4.76±0.10(Predicted)
color 
White
CAS DataBase Reference
35700-23-3(CAS DataBase Reference)
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Carboprost Usage And Synthesis

Description

15(S)-15-methyl PGF2α is a metabolically stable analog of PGF2α. It is a potent uterine stimulant and abortifacient which can be administered intramuscularly to induce labor. It induces luteolysis and reduces serum progesterone concentrations when given as an intramuscular injection in non-pregnant rhesus monkeys.

Chemical Properties

Off- White Solid

Uses

Analog of prostaglandin F2α. Oxytocic.

Uses

Analog of prostaglandin F2a. Oxytocic

Definition

ChEBI: Prostaglandin F2alpha in which the hydrogen at position 15 is substituted by methyl (S configuration). It is used as an abortifacient agent that is effective in both the first and second trimesters of regnancy.

brand name

Hemabate (Pharmacia & Upjohn).

CarboprostSupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Email
info@chemvon.com
LGM Pharma
Tel
1-(800)-881-8210
Email
inquiries@lgmpharma.com
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Email
sales@sunlidabio.com
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