1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE Chemical Properties

Melting point:

168-170 °C (lit.)

Boiling point:

347.0±27.0 °C(Predicted)

Density 

1.308±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Dichloromethane, Ethyl Acetate, Methanol

form 

Solid

pka

8.09±0.18(Predicted)

color 

Brown

CAS DataBase Reference

6178-42-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

2904200090

MSDS

• Language:English Provider:SigmaAldrich

1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE Usage And Synthesis

Chemical Properties

Brown Solid

Uses

β-Nitrostyrene derivative, with inhibitory activity of Src and/or Syk kinase and antibacterial activity.

Uses

trans-4-Hydroxy-3-methoxy-β-nitrostyrene may be used in the synthesis of cytotoxic β-nitrostyrene derivatives, 4-O-benzoyl-3-methoxy-β-nitrostyrene (BMNS) derivatives.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 2781, 1950 DOI: 10.1021/ja01162a521

General Description

trans-4-Hydroxy-3-methoxy-β-nitrostyrene is a phenolic β-nitrostyrene. Synthesis of 4-hydroxy-3-methoxy-β-nitrostyrene is reported.

1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE(6178-42-3)Related Product Information

• 3,4-Methylenedioxy-beta-nitrostyrene
• 1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE
• 3,4-DIMETHOXY-B-NITROSTYRENE
• 4-Hydroxystyrene
• Nitroethylene
• MNP-GLC
• 5-(2-NITROPROP-1-ENYL)-1,3-BENZODIOXOLE
• 3,4-DIMETHOXY-BETA-METHYL-BETA-NITROSTYRENE
• MNP-GAL
• TRANS-3-BENZYLOXY-4-METHOXY-BETA-NITROSTYRENE
• 4-BENZYLOXY-3-METHOXY-OMEGA-NITROSTYRENE
• 1-(3,4,5-TRIMETHOXYPHENYL)-2-NITROETHENE
• 1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROPROPENE
• 1-(5-BROMO-2-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE
• 1-(3-HYDROXY-4-METHOXYPHENYL)-2-NITROETHENE
• 1-(4-ETHOXY-3-METHOXYPHENYL)-2-NITROPROPENE
• 1-(3,4-(METHYLENEDIOXY)-6-NITROPHENYL)-2-NITROETHENE
• 4-BENZYLOXY-3-METHOXY-6-B-DINITROSTYRENE