1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Basic information
- Product Name:
- 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
- Synonyms:
-
- 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid hydrochloride
- 3-pyridinecarboxylicacid,1,2,5,6-tetrahydro-1-(2-(bis(4-(trifluoromethyl)phen
- ci966
- CI 966 HYDROCHLORIDE
- 1-[2-[BIS(4-(TRIFLUOROMETHYL)PHENYL)METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID
- 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
- 1-[2-bis[4-(Trifluormethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine3-carboxylic acid hydrochloride
- CI 966 hydrochlorid
- CAS:
- 110283-66-4
- MF:
- C23H22ClF6NO3
- MW:
- 509.87
- Product Categories:
-
- GABA/Glycine receptor
- Mol File:
- 110283-66-4.mol
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1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Chemical Properties
- Melting point:
- 240-244 °C
- storage temp.
- Desiccate at RT
- solubility
- Soluble to 10 mM in ethanol and to 100 mM in DMSO
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1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Usage And Synthesis
Uses
CI-966 Hydrochloride is highly selective for the cloned GABA transporter GAT-1. CI 966 Hydrochloride is a GABA transport inhibitor.
Biological Activity
Selective inhibitor of the GABA transporter GAT-1 (IC 50 values are 0.26 and 1.2 μ M at cloned human and rat GAT-1 respectively). Displays over 200-fold selectivity over GAT-2 and GAT-3. Centrally active upon systemic administration in vivo . Anticonvulsive and neuroprotective.
storage
Desiccate at RT
1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDESupplier
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- 821-50328103-801 18930552037
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- Tel
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1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE(110283-66-4)Related Product Information
- GUVACINE HYDROCHLORIDE
- 1-[4-(TRIFLUOROMETHYL)PHENYL]ETHANOL
- 4,4'-DIMETHYLBENZHYDROL
- (S)-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHANOL
- 1-BENZYL-4-TRIFLUOROMETHYLBENZENE
- CHEMBRDG-BB 4017707
- 2-DIETHYLAMINOMETHYL-ACRYLIC ACID
- ARECAIDINE HYDROCHLORIDE
- 4-(TRIFLUOROMETHYL)BENZHYDROL
- 4,4'-BIS(TRIFLUOROMETHYL)BENZHYDROL
- (R)-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHANOL
- 4-Methylbenzhydrol
- 4,4'-BIS(TRIFLUOROMETHYL)DIPHENYLMETHANE
- 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE