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Arctiin

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Arctiin Basic information

Product Name:
Arctiin
Synonyms:
  • ARCTIGENIN-O-BETA-D-GLUCOPYRANOSIDE
  • (-)-ARCTIIN
  • ARCTIIN
  • ARCTIIN:2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]-3-[[4-(-D-GLUCOPYRANOSYLOXY)-3-METHOXYPHENYL]METHYL]DIHYDRO-, (3R,4R)-,
  • ARCTIIN(P)
  • (-)-Arctin,Arctiumlappa
  • 2 (3H)-Furanone, 4-[(3, 4-dimethoxyphenyl)methyl]-3-[[4-(.beta.-D-gluc opyranosyloxy)-3-met hoxyphenyl]methyl]dihydro-, (3R-trans)-
  • 2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]-3-[[4-(-D-GLUCOPYRANOSYLOXY)-3-METHOXYPHENYL]METHYL]DIHYDRO-, (3R,4R)-
CAS:
20362-31-6
MF:
C27H34O11
MW:
534.55
Product Categories:
  • Miscellaneous Natural Products
  • Natural Plant Extract
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
Mol File:
20362-31-6.mol
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Arctiin Chemical Properties

Melting point:
107.0 to 111.0 °C
Boiling point:
756.4±60.0 °C(Predicted)
Density 
1.363±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
White to off-white solid.
pka
12.83±0.70(Predicted)
color 
White to Off-White
λmax
278nm(EtOH)(lit.)
InChIKey
XOJVHLIYNSOZOO-SWOBOCGESA-N
SMILES
[C@@H]1(COC(=O)[C@@H]1CC1=CC=C(O[C@H]2[C@H](O)[C@H]([C@H](O)[C@@H](CO)O2)O)C(OC)=C1)CC1=CC=C(OC)C(OC)=C1 |&1:0,5,12,13,15,16,18,r|
LogP
-0.564 (est)
CAS DataBase Reference
20362-31-6(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HS Code 
29389090
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Arctiin Usage And Synthesis

Uses

Arctiin is a phytochemical acting as a UV filter. It protects against UVB radiation exposure.

Definition

ChEBI: Arctiin is a glycoside and a lignan.

Biological Activity

Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used alone or in combination with oseltamivir. Arctiin plays an important role in the process of inflammation, by preventing the release of nitric oxide, prostaglandin E2, TNF-α (tumor necrosis factor - α), interleukin (IL)-1β and IL-6. A study using r at model shows th at arctiin possess anti-diabetic activity and might serve as an inhibitor of diabetic retinopathy.', 'Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used along or in combination with oseltamivir.

ArctiinSupplier

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