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4-(ChloroMercuri)benzenesulfonic Acid SodiuM Salt

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4-(ChloroMercuri)benzenesulfonic Acid SodiuM Salt Basic information

Product Name:
4-(ChloroMercuri)benzenesulfonic Acid SodiuM Salt
Synonyms:
  • P-CHLOROMERCURIPHENYLSULFONIC ACID
  • PCMBS
  • 4-(chloromercuri)benzenesulfonic acid monosodium salt
  • P-chloromercuriphenylsulfonic acid*monosodium
  • sodium 4-(chloromercurio)benzenesulphonate
  • 4-(Chloromercuri)benzenesulfonic ,sodium salt
  • 4-(CHLOROMERCURI)BENZENESULFONIC ACID, SODIUM SALT
  • p-Chloromercuriphenylsulfonic Acid, PCMBS
CAS:
14110-97-5
MF:
C6H4ClHgNaO3S
MW:
415.19
Product Categories:
  • MTS and Sulfhydryl Active Reagents
  • MTS & Sulfhydryl Active Reagents
  • Aromatics
Mol File:
14110-97-5.mol
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4-(ChloroMercuri)benzenesulfonic Acid SodiuM Salt Chemical Properties

Melting point:
>370°C
storage temp. 
Amber Vial, -20°C Freezer
solubility 
DMSO (Slightly, Heated), Water (Slightly)
form 
Solid
color 
Off-White to Light Grey
Stability:
Store at -20°C
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Safety Information

Hazard Codes 
T
RIDADR 
2025
Hazard Note 
Toxic
HazardClass 
6.1(a)
PackingGroup 
II
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4-(ChloroMercuri)benzenesulfonic Acid SodiuM Salt Usage And Synthesis

Chemical Properties

Off-White Powder

Uses

A useful sulfhydryl reagent, 4-(ChloroMercuri)benzenesulfonic Acid SodiuM Salt reacts with Histidine 225C, a residue of the NhaA-Na/H Antiporter of Escherichia Coli. More soluble than p-chloromercuribenzoic acid

Purification Methods

The free acid is obtained by acidifying an aqueous solution, filtering off the acid, washing it with H2O and recrystallising from hot H2O to give a colourless solid which is dried in a vacuum over P2O5 and should be free of Cl-ions (AgNO3 test). The Na salt is made by dissolving it in one equivalent of aqueous NaOH and evaporating to dryness. [Nesmejanow et al. Chem Ber 67 130 1934, Boyer J Am Chem Soc 76 4331 1954.] HIGHLY TOXIC.

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