Basic information Safety Supplier Related

C-ATR

Basic information Safety Supplier Related

C-ATR Basic information

Product Name:
C-ATR
Synonyms:
  • C-ATR, CAT
  • 33286-30-5 (Di-potassium salt)
  • Carboxyatractylate
  • Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-((2-o-(3-methyl-1-oxobutyl)-3,4-di-o-sulfo-alpha-D-glucopyranosyl)oxy)-, (2beta,15alpha)-
  • CAT
  • C-ATR
  • CARBOXYATRACTYLOSIDE
  • CARBOXYATRACTYLOSIDE, ATRACTYLIS GUMMIFERA
CAS:
35988-42-2
MF:
C31H46O18S2
MW:
770.82
Mol File:
35988-42-2.mol
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C-ATR Chemical Properties

Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Water: 10 mg/ml
form 
White solid
pka
-3?+-.0.18(Predicted)
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Safety Information

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
36/37-45
RIDADR 
UN 2811 6.1/PG 1
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C-ATR Usage And Synthesis

Uses

Carboxyatractyloside is a derivative of Atractyloside (A794530), a specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in permeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane.

C-ATRSupplier

Sigma-Aldrich
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