3,5-Dibromobenzoic acid Chemical Properties

Melting point:

218-220 °C (lit.)

Boiling point:

355.2±32.0 °C(Predicted)

Density 

1.9661 (rough estimate)

refractive index 

1.4970 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Very faint turbidity in methanol.

form 

powder to crystal

pka

3.42±0.10(Predicted)

color 

White to Light yellow

BRN 

1940691

CAS DataBase Reference

618-58-6(CAS DataBase Reference)

NIST Chemistry Reference

3,5-Dibromobenzoic acid(618-58-6)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

RTECS 

DG6290010

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3,5-Dibromobenzoic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

3,5-Dibromobenzoic acid may be used for the syntheses (+)-menthyl 3,5-dibromobenzoate, di-tert-butyl 4-[2-(tert-butoxycarbonyl)ethyl]-4-(3,5-dibromobenzamido)heptanedioate2, (L)-methyl 2-(3,5-dibromobenzamido)-3-phenylpropanoate.

General Description

3,5-Dibromobenzoic acid is 3,5-dibromo-substituted benzoic acid.

Synthesis

3,5-Dibromobenzoic acid was synthesized from anthranilic acid by bromination, diazotization and additional reactions derived. The bromination reaction is carried out at about 20°C. After the reaction, the crystals are filtered, washed with hot water to remove anthranilic acid and hydrochloric acid, and recrystallized with acetic acid to obtain o-amino-3,5-dibromobenzoic acid; then use sodium nitrite to carry out diazotization in hydrochloric acid at about 0°C, then add the diazonium salt into ethanol containing calcium sulfate at 60-70°C in batches. After the addition is complete, continue stirring for 10 minutes, filter to obtain the crude product, and recrystallize with ethanol to obtain the finished product.

3,5-Dibromobenzoic acid(618-58-6)Related Product Information

• Folic acid
• Citric acid
• 2,2-Bis(bromomethyl)propane-1,3-diol
• Ethyl 2-(Chlorosulfonyl)acetate
• 1,2-DIBROMOETHYLENE
• 2,4-DIBROMOPENTANE
• 2,3-Dibromopropionic acid
• 1,2-Dibromopropane
• meso-2,3-Dibromosuccinic acid
• 1,3-Dibromo-5,5-dimethylhydantoin
• 1,3-Bis(bromomethyl)benzene
• DBDCB
• Ascoric Acid
• 2,4-DIBROMOBENZOIC ACID
• 3,5-DIBROMO-4-METHYLBENZOIC ACID
• 2-HYDROXY-3,5-DIBROMOBENZOIC ACID
• 4-HYDROXY-3,5-DIBROMOBENZOIC ACID
• Tetrabromo-2-sulfobenzoic acid cyclic anhydride