Nicotine ditartrate Chemical Properties

Melting point:

90°

alpha 

D20 +26° (c = 10)

storage temp. 

Desiccate at RT

solubility 

H₂O: 50 mg/mL

form 

powder

color 

white to off-white

optical activity

[α]/D +20 to +26°, c = 1.0 in water

InChIKey

RFEJUZJILGIRHQ-UHFFFAOYSA-N

CAS DataBase Reference

65-31-6(CAS DataBase Reference)

EPA Substance Registry System

Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (65-31-6)

Safety Information

Hazard Codes 

T+,N

Risk Statements 

26/27/28-51/53

Safety Statements 

13-28-45-61

RIDADR 

UN 1659 6.1/PG 2

WGK Germany 

2

RTECS 

QT0350000

HazardClass 

6.1(a)

PackingGroup 

II

Hazardous Substances Data

65-31-6(Hazardous Substances Data)

MSDS

• Language:English Provider:3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate
• Language:English Provider:SigmaAldrich

Nicotine ditartrate Usage And Synthesis

Uses

nicotinyl acetylchloline receptor agonist, ectoparasiticide

Uses

cathartic, laxative

General Description

Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.

Biological Activity

Nicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo .

Biochem/physiol Actions

Product does not compete with ATP.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and CO. See also NICOTINE.

storage

Desiccate at RT

Nicotine ditartrate(65-31-6)Related Product Information

• L-Carnitine-L-tartrate
• Pyridine
• D(-)-Tartaric acid
• Metoprolol tartrate
• L(+)-Tartaric acid
• Povidone iodine
• Nicotinic acid
• Polyvinylpyrrolidone
• N-Vinyl-2-pyrrolidone
• N-Methyl-2-pyrrolidone
• Pyrrolidine
• Dibenzoyltartaric acid
• METHYL-2-PYRROLIDONE
• Nicotine
• (+)-NICOTINE
• NICOTINE BI-L-(+)-TARTRATE
• Nicotine ditartrate