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QUINIDINE GLUCONATE

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QUINIDINE GLUCONATE Basic information

Product Name:
QUINIDINE GLUCONATE
Synonyms:
  • 6’-methoxy-cinchonan-9-o(9s)-cinchonan-9-omono-d-gluconate(salt)
  • compd.withquinidine(1:1),d-gluconicaci
  • d-gluconicacid,compd.with(9s)-6’-methoxycinchonan-9-ol(1:1)
  • quinidinemono-d-gluconate(salt)
  • QUINIDINE GLUCONATE
  • QUINIDINE GLUCONATE SALT
  • QUINIDINEGLUCONATE,USP
  • Quinidine Gluconate (200 mg)
CAS:
7054-25-3
MF:
C26H36N2O9
MW:
520.57
EINECS:
230-333-9
Product Categories:
  • Neat CompoundsAnalytical Standards
  • Alphabetic
  • Drugs&Metabolites
  • Forensic and Veterinary Standards
  • Q
Mol File:
7054-25-3.mol
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QUINIDINE GLUCONATE Chemical Properties

Melting point:
175-176 C
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
36-26
RIDADR 
1544
WGK Germany 
3
RTECS 
LZ5250000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2939200050
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QUINIDINE GLUCONATE Usage And Synthesis

Uses

Cardiac depressant (anti-arrhythmic).

Uses

Quinidine Gluconate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.

Definition

ChEBI: Quinidine D-gluconate is a D-gluconate adduct. It is functionally related to a quinidine.

brand name

Duraquin (Warner Chilcott); Quinaglute (Berlex).

General Description

Quinidinium gluconate(Duraquin, Quinaglute) occurs as an odorless, very bitter,white powder. In contrast with the sulfate salt, it is freelysoluble in water. This is important because there are emergencieswhen the condition of the patient and the need for arapid response make the oral route of administration inappropriate.The high water solubility of the gluconate saltalong with a low irritant potential makes it valuable when aninjectable form is needed in these emergencies. Quinidinegluconate forms a stable aqueous solution. When used for injection, it usually contains 80 mg/mL, equivalent to 50 mgof quinidine or 60 mg of quinidine sulfate.

Veterinary Drugs and Treatments

Quinidine is used in small animal or equine medicine for the treatment of ventricular arrhythmias (VPCs, ventricular tachycardia), refractory supraventricular tachycardias, and supraventricular arrhythmias associated with anomalous conduction in Wolff- Parkinson-White (WPW) syndrome. Chronic use of quinidine for controlling ventricular arrhythmias and supraventricular tachycardia in dogs has diminished over the years as other drugs appear to be more effective. It is still used in dogs and horses to convert atrial fibrillation to sinus rhythm. Oral therapy is generally not used in cats.

QUINIDINE GLUCONATESupplier

Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
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Shanghai Qiao Chemical Science Co., Ltd
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021-58892003
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info@qiaochem.com
Beijing Solarbio Science & Tecnology Co., Ltd.
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010-50973186 4009686088
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3193328036@qq.com
Alfa Chemistry
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Dayang Chem (Hangzhou) Co.,Ltd.
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571-88938639 +8617705817739
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