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DIETHYL (PHTHALIMIDOMETHYL)PHOSPHONATE

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DIETHYL (PHTHALIMIDOMETHYL)PHOSPHONATE Basic information

Product Name:
DIETHYL (PHTHALIMIDOMETHYL)PHOSPHONATE
Synonyms:
  • DIETHYL (PHTHALIMIDOMETHYL)PHOSPHONATE
  • (PHTHALIMIDOMETHYL)PHOSPHONIC ACID DIETHYL ESTER
  • LABOTEST-BB LT00452168
  • Diethyl(phtalimidomethyl)phosphonate, 98+ %
  • Diethyl(phthalimidomethyl)phosphonate,97%
  • Diethyl Phthalimidomethyl Phosphate
  • Diethyl (phtalimidomethyl)phosphonate
  • diethyl ((1,3-dioxoisoindolin-2-yl)Methyl)phosphonate
CAS:
33512-26-4
MF:
C13H16NO5P
MW:
297.24
Product Categories:
  • Horner-Emmons Reaction
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
  • Synthetic Organic Chemistry
  • Wittig & Horner-Emmons Reaction
  • C-C Bond Formation
  • Horner-Wadsworth-Emmons Reagents
  • Olefination
Mol File:
33512-26-4.mol
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DIETHYL (PHTHALIMIDOMETHYL)PHOSPHONATE Chemical Properties

Melting point:
60-64 °C(lit.)
Boiling point:
423.3±28.0 °C(Predicted)
Density 
1.312±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
solid
pka
-2.49±0.20(Predicted)
color 
White to Almost white
InChI
InChI=1S/C13H16NO5P/c1-3-18-20(17,19-4-2)9-14-12(15)10-7-5-6-8-11(10)13(14)16/h5-8H,3-4,9H2,1-2H3
InChIKey
IUZMHUAHKBHJFY-UHFFFAOYSA-N
SMILES
P(CN1C(=O)C2=C(C1=O)C=CC=C2)(=O)(OCC)OCC
CAS DataBase Reference
33512-26-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45-24/25
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HS Code 
29337900

MSDS

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DIETHYL (PHTHALIMIDOMETHYL)PHOSPHONATE Usage And Synthesis

Chemical Properties

WHITE TO OFF-WHITE CRYSTALLINE POWDER

Uses

Reacant for:

  • Horner-Wadsworth-Emmons reactions
  • Preparation of macrocyclic phosphorous acid analogs as inhibitors of HCV-NS3 protease
  • Synthesis of dendrimer-based pH-responsive MRI contrast agent

Synthesis Reference(s)

Synthesis, p. 909, 1994 DOI: 10.1055/s-1994-25599

reaction suitability

reaction type: C-C Bond Formation

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