ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Esters > Ethyl compound > Diethyl methylmalonate
Diethyl methylmalonate
Diethyl methylmalonate Basic information
- Product Name:
- Diethyl methylmalonate
- Synonyms:
-
- RARECHEM AL BI 0301
- Diethyl methylmalonate 99%
- METHYLMALONIC ACID DIETHYL ESTER
- DIETHYL METHYLMALONATE
- DIETHYL 2-METHYLPROPANEDIOATE
- 1,3-Diethyl 2-methylpropanedioate
- Diethyl methylmalote
- Methoxymalonic Acid Diethyl Ester
- CAS:
- 609-08-5
- MF:
- C8H14O4
- MW:
- 174.19
- EINECS:
- 210-175-7
- Product Categories:
-
- Building Blocks
- C8 to C9
- Carbonyl Compounds
- Chemical Synthesis
- Esters
- Organic Building Blocks
- Pharmaceutical Intermediates
- Cyanoacetic acid esters
- Hydrocyanic acid derivatives
- bc0001
- Mol File:
- 609-08-5.mol
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Diethyl methylmalonate Chemical Properties
- Boiling point:
- 198-199 °C (lit.) 78-80 °C/10 mmHg
- Density
- 1.022 g/mL at 20 °C (lit.)
- refractive index
- n20/D 1.413(lit.)
- Flash point:
- 170 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 1000mg/l
- form
- Liquid
- pka
- 13.13±0.46(Predicted)
- Specific Gravity
- 1.013
- color
- Clear colorless
- PH
- 8 (1000mg/l, H2O, 20℃)
- Water Solubility
- immiscible
- BRN
- 637028
- InChIKey
- UPQZOUHVTJNGFK-UHFFFAOYSA-N
- LogP
- 1.256 (est)
- CAS DataBase Reference
- 609-08-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Propanedioic acid, methyl-, diethyl ester(609-08-5)
- EPA Substance Registry System
- Propanedioic acid, methyl-, diethyl ester (609-08-5)
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Safety Information
- Safety Statements
- 23-24/25
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29171990
MSDS
- Language:English Provider:Diethyl methylmalonate
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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Diethyl methylmalonate Usage And Synthesis
Chemical Properties
Clear liquid
Uses
Diethyl methylmalonate is used as intermediate for the syntheses of pharmaceuticals, e.g. non-steroidal anti-inflammatory agents with 2-acrylpropionic acid structures acrylpropionic acid structure. It is also used in the flavour and fragrance industries. Product Data Sheet
Uses
Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain.
General Description
Diethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis.
Diethyl methylmalonate Preparation Products And Raw materials
Preparation Products
2,5-Dimethylpyridine4,6-DIHYDROXY-5-METHYLPYRIMIDINE7-CHLORO-4-HYDROXY-3-QUINOLINECARBOXYLIC ACIDethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate
Raw materials
Diethyl methylmalonateSupplier
TAIZHOU DKD CHEMICAL CO., LTD. Gold
- Tel
- 0576-89700933 18657652963
- yf.chen@tzdkdchem.com
Dongyang Baihang Chemical Co., Ltd. Gold
- Tel
- 0579-86886233 18006543966
- 355093164@qq.com
Hangzhou Xingui Industrial Co., Ltd. Gold
- Tel
- 0571-86692169 18958109620
- nc@newgainer.com
Nanjing Dilu Pharmaceutical Co., Ltd Gold
- Tel
- 18014482516
- 977144864@qq.com
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. Gold
- Tel
- 133-96369453 18678026865
- sdfantai@163.com
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Diethyl methylmalonate(609-08-5)Related Product Information
- 2-Methylpropanedioic acid
- 2,4-Difluoronitrobenzene
- flurbiprofen
- 4-Acetyl-2-fluorobiphenyl
- Flurbiprofen Impurity 8
- Flurbiprofen Impurity 15
- 2,4-Difluorobiphenyl
- diethyl (3-fluoro-4-nitrophenyl)methylmalonate
- 4'-hydroxyflurbiprofen
- 2-Fluorobiphenyl-4-carboxylic Acid
- Flurbiprofen Impurity
- Flurbiprofen Related Impurity 1
- 4-ETHYL-2-FLUORO-1,1'-BIPHENYL
- diethyl (4-amino-3-fluorophenyl)methylmalonate
- Flurbiprofen Impurity 16
- (2-FLUORO-4-BIPHENYL)ACETIC ACID
- α-Hydroxy Flurbiprofen
- 3-Fluoro-4-phenylphenol