3,3-Dimethylglutaric acid Chemical Properties

Melting point:

100-102 °C (lit.)

Boiling point:

290 °C

Density 

1,42 g/cm³

refractive index 

1.4336 (estimate)

Flash point:

89-90°C/2mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Fine Crystalline Powder

pka

pK1:3.70;pK2:6.34 (25°C)

color 

White to beige

Water Solubility 

soluble

BRN 

1765439

InChIKey

DUHQIGLHYXLKAE-UHFFFAOYSA-N

CAS DataBase Reference

4839-46-7(CAS DataBase Reference)

NIST Chemistry Reference

3,3-Dimethylglutaric acid(4839-46-7)

EPA Substance Registry System

Pentanedioic acid, 3,3-dimethyl- (4839-46-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HS Code 

29171990

MSDS

• Language:English Provider:2,2-Dimethylpropane-1,3-dicarboxylic acid
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3,3-Dimethylglutaric acid Usage And Synthesis

Chemical Properties

white to beige fine crystalline powder

Uses

3,3-Dimethylglutaric Acid is a versatile reactant used in the synthesis of (+)-Hirsutene via catalytic asymmetric transannular aldolization.

Uses

Reactant involved in:

• Cyclodehydration of diols
• Synthesis of conjugates of betulin derivatives used as anti-HIV agents
• Preparation of dimeric peptide antagonists of IgG-FcRn interaction
• Microwave-assisted protection of glutaraldehyde
• Synthesis of glycyrrhetinic acid derivatives for proteasome inhibition
• Catalytic, asymmetric transannular aldolizations

Uses

3,3-Dimethylglutaric acid can be used as reactant involved in: Cyclodehydration of diols; Synthesis of conjugates of betulin derivatives used as anti-HIV agents; Preparation of dimeric peptide antagonists of IgG-FcRn interaction; Microwave-assisted protection of glutaraldehyde; Synthesis of glycyrrhetinic acid derivatives for proteasome inhibition; Catalytic, asymmetric transannular aldolizations.

Definition

ChEBI: An alpha,omega-dicarboxylic acid that is glutaric acid substituted by two methyl groups at the C-3 position.

3,3-Dimethylglutaric acid(4839-46-7)Related Product Information

• 2-Ketoglutaric acid
• N,N-Dimethylformamide
• Dimethyl sulfoxide
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• Ethyl 2-(Chlorosulfonyl)acetate
• Glutaric acid
• OXALIC ACID
• Poly(dimethylsiloxane)
• Ascoric Acid
• (1S)-(-)-Camphanic acid
• Cyclopentane-1,1-diacetic acid
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• 3-ETHYL-3-METHYLGLUTARIC ACID
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• (1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID
• 2,2-DIMETHYLGLUTARIC ACID, 98+%,ALPHA,ALPHA-DIMETHYLGLUTARIC ACID,2,2-DIMETHYLGLUTARIC ACID