6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE Chemical Properties

Boiling point:

414.1±25.0 °C(Predicted)

Density 

1.830±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

10.82±0.40(Predicted)

form 

solid

color 

Brown

Safety Information

HS Code 

2933998090

6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE Usage And Synthesis

Uses

6-Bromo-1H-indazole-3-carbaldehyde is an indazole compound, mostly used in chemical manufacturing or pharmaceutical intermediate components.

Synthesis

6-Bromo-1H-indazole-3-carbaldehyde is prepared by the reaction of 6-Bromoindole and acetone. The specific synthesis steps are as follows:
To 70g is added in an aqueous solution of sodium nitrite of 20g 6-bromoindole acetone: water (200 ml: 200 ml) solution; room temperature, in to the system by adding 2N HCl solution to pH to 2.5 the left and right; 20 min the rear, with a red brown gas desorbing, slabs system has; 10 min later, TLC detection material disappears, cessation of the reaction, adding to system 1.0L ethyl acetate (EA), two-phase separation, the organic phase with saturated sodium bicarbonate (500 ml * 2) washing, drying organic anhydrous magnesium sulfate, concentrated to obtain 22g compound 2, as a black solid.

6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE(885271-72-7)Related Product Information

• 6-BROMO INDAZOLE-3-CARBOXYLIC ACID
• 6-BROMO-(1H)INDAZOLE-4-CARBOXYLIC ACID
• 6-BROMO-1H-PYRAZOLO[4,3-B]PYRIDIN-3-AMINE
• 6-bromo-1H-indazole-5-carboxylic acid
• Methyl 6-broMo-1H-indazole-5-carboxylate
• ETHYL 6-BROMO-1H-INDAZOLE-3-CARBOXYLATE
• METHYL 6-BROMO-1H-INDAZOLE-3-CARBOXYLATE
• 6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE
• 5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE, 95+%,5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE
• 1H-INDAZOLE-3-CARBALDEHYDE
• 3 ALDEHYDE, 4-METHYL ESTER, 6-BROMOINDAZOLE
• 6-BROMO-4-IODO-3-(1H)INDAZOLE CARBOXALDEHYDE
• 6-BROMO-4-METHYL-3-(1H)INDAZOLE CARBOXYLIC ACID
• 6-BROMO-4-IODO-3-(1H)INDAZOLE CARBOXYLIC ACID
• 4,6-DIBROMO-1H-INDAZOLE-3-CARBOXALDEHYDE
• 6-BROMO-4-METHOXY-3-(1H)INDAZOLE CARBOXALDEHYDE
• 6-BROMO-4-FLUORO-3-(1H)INDAZOLE CARBOXYLIC ACID
• 6-BROMO-3-FORMYL-4-INDAZOLECARBOXYLIC ACID