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L-NORADRENALINE BITARTRATE

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L-NORADRENALINE BITARTRATE Basic information

Product Name:
L-NORADRENALINE BITARTRATE
Synonyms:
  • (-)-noradrenalineacidtartrate
  • (-)-noradrenalinebitartratemonohydrate
  • Noradrenalineacidtartrate
  • noradrenalinehydrogentartrate
  • noradrenalinetartrate
  • norepinephrinehydrogentartrate
  • L-NORADRENALINE BITARTRATE
  • L-4-(A-HYDROXY-B-AMINOETHYL)CATECHOL BITARTRATE
CAS:
51-40-1
MF:
C8H11NO3.C4H6O6
MW:
319.26
EINECS:
200-095-0
Product Categories:
  • Standards - 13C & 2H for GC-Mass Spectrometry
Mol File:
51-40-1.mol
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L-NORADRENALINE BITARTRATE Chemical Properties

storage temp. 
Store at 4°C, protect from light
solubility 
31.93mg/mL in DMSO
pka
8.64(at 25℃)
Melting point:
102-104 °C
Water Solubility 
31.93mg/mL in Water
CAS DataBase Reference
51-40-1(CAS DataBase Reference)
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Safety Information

RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 ivn-rat: 210 mg/kg YACHDS 7,627,79
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L-NORADRENALINE BITARTRATE Usage And Synthesis

Uses

Adrenergic (vasoconstrictor).

brand name

Levophed (Hospira).

Clinical Use


Hypotension
Cardiac arrest (sympathomimetic)

Safety Profile

Poison by intravenous andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.

Drug interactions

Potentially hazardous interactions with other drugs
Adrenergic neurone blockers: antagonise hypotensive effect.

Anaesthetics: increased risk of arrhythmias with volatile general anaesthetics.

Antidepressants: tricyclics may cause hypertension and arrhythmias; MAOIs and moclobemide may cause hypertensive crisis.

Beta-blockers: can cause severe hypertension.
Clonidine: possibly increased risk of hypertension.

Dopaminergics: effects possibly increased by entacapone; avoid with rasagiline.

Sympathomimetics: effects possibly enhanced by dopexamine.

Metabolism

Extensively metabolised by catechol-O-methyltransferase (COMT), and monoamine oxidase (MAO).
Up to 16% of an intravenous dose is excreted unchanged in the urine with methylated and deaminated metabolites in free and conjugated forms.

storage

Store at +4°C

L-NORADRENALINE BITARTRATESupplier

Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
GIHI CHEMICALS CO.,LTD
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0086-571-86217390
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Sales@gihichem.com
HBCChem, Inc.
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+1-510-219-6317
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sales@hbcchem.com
Chengdu HuaXia Chemical Reagent Co. Ltd
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400-1166-196 13458535857
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cdhxsj@163.com
Chizhou Kailong Import and Export Trade Co., Ltd.
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Email
xg01_gj@163.com