- Product Name:
- Propantheline bromide
- Product Categories:
- Drug bulk
- Intermediates & Fine Chemicals
- Mol File:
Propantheline bromide Chemical Properties
- Melting point:
- 1.2916 (rough estimate)
- refractive index
- 1.6200 (estimate)
- storage temp.
- H2O: soluble50mg/mL
- white to off-white
- Water Solubility
- >=10 g/100 mL at 21 ºC
- Stable. Combustible. Incompatible with strong oxidizing agents.
- EPA Substance Registry System
- Propantheline bromide (50-34-0)
- Language:English Provider:Propantheline bromide
Propantheline bromide Usage And Synthesis
white crystalline powder
Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.
A muscarinic acetylcholine receptor antagonist
Propantheline bromide,2-hydroxy-ethyl)diisopropylmethylammonium bromidexanthene-9-carboxylate (Pro-Banthine), is prepared in amanner exactly analogous to that used for methanthelinebromide. It is a white, water-soluble, crystalline substance,with properties quite similar to those of methantheline bromide.Its chief difference from methantheline bromide is inits potency, which has been estimated variously to be 2 to5 times as great.
White crystals or white powder. Melting point 159-161°C .Used therapeutically as an anticholinergic.
Air & Water Reactions
SYMPTOMS: Symptoms of exposure to Propantheline bromide include dilated pupils and blurred vision; increased intraocular tension and heart rate; hot, dry, red skin; dry mouth; disorientation; hallucinations; aggressive behavior; rapid pulse and respiration; convulsions; and coma.
Flash point data are not available for Propantheline bromide , but Propantheline bromide is probably combustible.
Veterinary Drugs and Treatments
In small animal medicine propantheline bromide has been used for its antispasmodic/antisecretory effects in the treatment of diarrhea. It is also employed in the treatment of hyperreflexic detrusor or urge incontinence and as oral treatment in anticholinergic responsive bradycardias. In horses, propantheline has been used intravenously to reduce colonic peristalsis and for relaxing the rectum to allow easier rectal examination and surgery.
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- ETHYLENEDIAMINE TETRAKIS(PROPOXYLATE-BLOCK-ETHOXYLATE) TETROL
- Allyl bromide
- Ethidium bromide
- Rocuronium bromide
- 5-Chlorovaleric acid
- 3-Bromopropylamine hydrobromide
- Sodium bromate
- Methyl 2-hydroxyethyl cellulose
- Diphenolic acid
- Tetrapropylammonium bromide
- Hydroxyethyl Cellulose
- Hydroxyethyl starch