L-Phenylglycinol
L-Phenylglycinol Basic information
- Product Name:
- L-Phenylglycinol
- Synonyms:
-
- ((1S)-1-HydroxyMethyl-2-phenylethyl)aMine
- (2S)-2-AMino-3-phenyl-1-propanol
- (S)-(-)-2-AMino-3-phenyl-1-glycinol
- (S)-2-AMino-1-hydroxy-3-phenylpropane
- (βS)-β-AMino-benzenepropanol
- (S)-(-)-2-AMINO-3-PHENYL-1-PROPANOL FOR
- (S)-3-Phenyl-2-aMino-1-propanol
- 1-Propanol, 2-aMino-3-phenyl-, L- (8CI)
- CAS:
- 3182-95-4
- MF:
- C9H13NO
- MW:
- 151.21
- EINECS:
- 221-674-4
- Product Categories:
-
- Chiral Reagents
- Intermediates & Fine Chemicals
- chiral
- Chiral Reagent
- Pharmaceuticals
- Intermediates
- Pharmaceutical Intermediates
- Amino Alcohols
- Phenylalanine [Phe, F]
- Amino Alcohols (Chiral)
- Chiral Building Blocks
- for Resolution of Acids
- Benzene derivatives
- Amino Acids & Derivatives
- Optical Resolution
- Synthetic Organic Chemistry
- Amino alcohols
- Mol File:
- 3182-95-4.mol
L-Phenylglycinol Chemical Properties
- Melting point:
- 92-94 °C(lit.)
- alpha
- -23 º (c=5,EtOH)
- Boiling point:
- 273.23°C (rough estimate)
- Density
- 1.0406 (rough estimate)
- refractive index
- -24.5 ° (C=5, EtOH)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Soluble in chloroform, ethyl acetate, ethanol and methanol.
- form
- Crystalline Powder
- pka
- 12.85±0.10(Predicted)
- color
- White to light yellow
- optical activity
- [α]22/D 22.8°, c = 1.2 in 1 M HCl
- Sensitive
- Air Sensitive
- BRN
- 2208238
- InChIKey
- STVVMTBJNDTZBF-VIFPVBQESA-N
- CAS DataBase Reference
- 3182-95-4(CAS DataBase Reference)
Safety Information
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45-24/25-27
- RIDADR
- UN 3259 8/PG 3
- WGK Germany
- 3
- RTECS
- UA6900000
- F
- 10-23
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29221980
MSDS
- Language:English Provider:L(-)-2-Amino-3-phenyl-1-propanol
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
L-Phenylglycinol Usage And Synthesis
Chemical Properties
white to light yellow crystal powder
Uses
Enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption.
Uses
Inhibits the intestinal absorption of Phenylalanine, making it a prospective treatment for phenylketonuria.
Uses
antiulcer
Definition
ChEBI: L-phenylalaninol is an amino alcohol resulting from the formal reduction of the carboxy group of L-phenylalanine to the corresponding alcohol. It is a member of amphetamines, an amino alcohol, a primary amino compound and a primary alcohol.
General Description
(S)-(-)-2-Amino-3-phenyl-1-propanol is a chiral amino alcohol.
Purification Methods
It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.]
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L-Phenylglycinol(3182-95-4)Related Product Information
- 3-Aminophenol
- Glycine
- Fosfomycin tromethamine
- ALTRENOGEST
- 6-Aminocaproic acid
- Tris(hydroxymethyl)aminomethane
- PHENYL VALERATE
- Phenprobamate
- Ketorolac tromethamine
- 1-Propanol
- (S)-(-)-2-Methyl-1-butanol
- TRISTEARIN
- (S)-4-Benzyl-2-oxazolidinone
- (R)-(-)-4-Phenyl-2-oxazolidinone
- (S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone
- Methyl L-phenylalaninate hydrochloride
- PHENYL RESIN
- 2-amino-3-(4-aminophenyl) propan-1-ol