Sclerotigenin Chemical Properties

Melting point:

235-238 °C

Density 

1.45±0.1 g/cm3(Predicted)

solubility 

DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble

form 

A solid

pka

11.90±0.20(Predicted)

Sclerotigenin Usage And Synthesis

Description

Sclerotigenin is a natural diazepine originally isolated from P. sclerotigenum that acts as an insect growth regulator. It reduces the growth rate of first instar H. zea larvae by 42% relative to controls when administered in the standard test diet at 200 ppm.

Uses

Sclerotigenin is an anti-insect benzodiazepine compound identified in Penicillium sclerotigenum (NRRL 3461). Sclerotigenin exhibits significant anti-insect activity against crop pest Helicoverpa zea[1].

References

[1] Joshi BK, et al. Sclerotigenin: A new antiinsectan benzodiazepine from the sclerotia of penicillium sclerotigenum. J Nat Prod. 1999 Apr;62(4):650-2. DOI:10.1021/np980511n