INSULIN-TRANSFERRIN SODIUM SELENITE
INSULIN-TRANSFERRIN SODIUM SELENITE Basic information
- Product Name:
- INSULIN-TRANSFERRIN SODIUM SELENITE
- Synonyms:
-
- INSULIN-TRANSFERRIN SODIUM SELENITE
- INSULIN-TRANSFERRIN-SODIUM SELENITE SUPPLEMENT
- MW:
- 0
- Mol File:
- Mol File
INSULIN-TRANSFERRIN SODIUM SELENITE Chemical Properties
- storage temp.
- 2-8°C
- form
- lyophilized
INSULIN-TRANSFERRIN SODIUM SELENITE Usage And Synthesis
Uses
The Insulin-Transferrin-Sodium Selenite Supplement is used in the cell culture media as a basal growth-factor supplement to which other cell type-specific nutrients and growth factors are added.
General Description
The insulin-transferrin-sodium selenite (ITS) supplement comprises three of the most crucial growth factors for many cell types. Insulin is a component of serum-free media formulations for all primary cells and cell lines. It stimulates cell growth, increases fatty acid and glycogen synthesis in a serum-free medium. Transferrin is an essential growth factor for many cell types. Selenium is very often necessary for optimal cell growth. ITS permits an appreciable reduction in serum requirements for cellular growth. ITS is also an antioxidant that supports the growth of in?vivo?derived (IVD) embryos. Insulin promotes embryonic growth and metabolism. The iron transport in the embryo is mediated by transferrin. Sodium selenite protects from oxidative damage and inhibits lipid peroxidation. ITS is useful in human chondrocytes monolayer culture.