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Swertiamarine
Swertiamarine Basic information
- Product Name:
- Swertiamarine
- Synonyms:
-
- (4ar-(4a-alpha,5-beta,6-alpha))-ranosyloxy)-4a-hydroxy
- 1h,3h-pyrano(3,4-c)pyran-1-one,4,4a,5,6-tetrahydro-5-ethenyl-6-(beta-d-glucopy
- 1H,3H-Pyrano[3,4-c]pyran-1-one,4,4.alpha.,5,6-tetrahydro-5-ethenyl-6-(.beta.-D-glucopyranosyloxy)-4.alpha.-hydroxy-,[4ar-(4.alpha.-.alpha.,5-.beta.,D-.alpha.)]-
- 3H-Pyrano[3,4-c]pyran-1-one,4,4.alpha.,5,6-tetrahydro-5-ethenyl-6-(.beta.-D-glucopyranosyloxy)-4.1H
- Swertiamari
- 4-c)pyran-1-one,4,4a,5,6-tetrahydro-5-ethenyl-6-(beta-d-glucopyranosyloxy)-4a-hydroxy-3h-pyrano(1
- glucopyranosyloxy)-4,4a,5,6-tetrahydro-4a-hydroxy-,(4aR,5R, 6S)-
- Swertiamarin(6CI,7CI,8CI)
- CAS:
- 17388-39-5
- MF:
- C16H22O10
- MW:
- 374.34
- Product Categories:
-
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Sugars, Carbohydrates & Glucosides
- Mol File:
- 17388-39-5.mol
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Swertiamarine Chemical Properties
- Melting point:
- 113-114°
- alpha
- D20 -127° (c = 1 in 96% ethanol)
- Boiling point:
- 649.3±55.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO : 250 mg/mL (667.84 mM; Need ultrasonic)
- form
- Solid
- pka
- 11.56±0.60(Predicted)
- color
- White to Yellow to Orange
- λmax
- 238nm(MeOH)(lit.)
- Merck
- 14,9010
- BRN
- 55278
- Stability:
- Hygroscopic
- InChIKey
- HEYZWPRKKUGDCR-QBXMEVCASA-N
- CAS DataBase Reference
- 17388-39-5(CAS DataBase Reference)
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Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- RTECS
- UQ1366700
- HS Code
- 29389090
- Toxicity
- mouse,LD50,intraperitoneal,> 8gm/kg (8000mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 464, 1982.
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Swertiamarine Usage And Synthesis
Uses
Swertimarine is an extract from Enicostemma littorale which is an herb used in the treatment of type 1 and 2 diabetes. Used to sensitize the cells to hypolipidemic conditions and insulin.
Definition
ChEBI: Swertiamarin is a glycoside.
Biological Activity
Swertiamarin has shown potential as antiatherogenic agent by inhibiting HMG-CoA reductase activity in high cholesterol fed rats. The high cholesterol fed rats treated with Swertiamarin showed prevention of increased serum total cholesterol, triglycerides, LDLs and VLDLs.
SwertiamarineSupplier
Henan Huaguang Biology Gold
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- 15893823597
- 2517544231@qq.com
Naturewill Biotechnology Co., Ltd. Gold
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- 028-82632533 18113192475
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Nanjing Dasf Biotechnology Co., Ltd. Gold
- Tel
- 025-+86-02585846866 +86-18094231287
- eric@dasfbio.com
Sichuan Hongen Plant Technology Co., Ltd. Gold
- Tel
- 17340288373
- victor.liu@hovane.com
Nanjing bingcheng Biotechnology Co., Ltd. Gold
- Tel
- 18805194892
- 2727751293@qq.com
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