4-HYDROXY-1-METHYL-2-QUINOLONE Chemical Properties

Melting point:

269-271 °C (lit.)

Boiling point:

306.47°C (rough estimate)

Density 

1.326

refractive index 

1.5060 (estimate)

pka

4.50±1.00(Predicted)

form 

powder to crystal

color 

Light yellow to Brown to Dark green

CAS DataBase Reference

1677-46-9(CAS DataBase Reference)

EPA Substance Registry System

2(1H)-Quinolinone, 4-hydroxy-1-methyl- (1677-46-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

FG7350000

Hazard Note 

Irritant

HS Code 

2933499090

Toxicity

mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01354,

MSDS

• Language:English Provider:SigmaAldrich

4-HYDROXY-1-METHYL-2-QUINOLONE Usage And Synthesis

Uses

4-Hydroxy-1-methyl-2(1H)-quinolone was used as nucleophile in electrochemical oxidation of catechols and the reaction was studied by cyclic voltammetry and controlled-potential coulometry. It was used in ceric ammonium nitrate-mediated oxidative cycloaddition of 1,3-dicarbonyls to conjugated compounds to yield substituted dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones and dihydrofurophenalenones. It was used in the synthesis of :

• 3-(4-methoxybenzyl)-4-hydroxy-1-methylquinolinone
• 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-hydroxy-1-methylquinolin-2(1H)-one
• 3-(4-chlorobenzyl)-4-hydroxy-1-methylquinolin-2(1H)-one
• 3,3′-bis(4-chlorobenzylidene)-1,10-methylquinolin-2,20-(1H)-one

4-HYDROXY-1-METHYL-2-QUINOLONE(1677-46-9)Related Product Information

• 4-HYDROXY-1-METHYL-2-QUINOLONE
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