Basic information Safety Supplier Related

(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane

Basic information Safety Supplier Related

(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Basic information

Product Name:
(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane
Synonyms:
  • (-)-(R,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
  • Nebivolol Impurity 19
  • Nebivolol Impurity 24
  • (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene
  • 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)-
  • (2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane
  • Nebivolol Impurity 7
  • 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)-
CAS:
197706-50-6
MF:
C11H11FO2
MW:
194.2
EINECS:
606-373-1
Mol File:
197706-50-6.mol
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(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Chemical Properties

Boiling point:
291.7±40.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
vapor pressure 
0.12-0.22Pa at 20-25℃
form 
Liquid:viscous
LogP
2.2-5.2 at 20℃ and pH7
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(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Usage And Synthesis

Uses

(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane is an intermediate to synthesize Nebivolol (rac, HCl salt, N387900) which is a β1-Adrenergic blocker.

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(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane(197706-50-6)Related Product Information