NYLIDRIN HYDROCHLORIDE
NYLIDRIN HYDROCHLORIDE Basic information
- Product Name:
- NYLIDRIN HYDROCHLORIDE
- Synonyms:
-
- NYLIDRIN HYDROCHLORIDE
- Nylidrin, HCl
- NYLIDRIN HYDROCHLORIDE B-ADRENERGIC AGON IST,
- NYLIDRIN HYDROCHLORIDE 95%
- Arlibide
- Arlidin
- Benzenemethanol, 4-hydroxy-.alpha.-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]-, hydrochloride
- Benzyl alcohol, p-hydroxy-.alpha.-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]-, hydrochloride
- CAS:
- 849-55-8
- MF:
- C19H26ClNO2
- MW:
- 335.87
- EINECS:
- 212-701-0
- Mol File:
- 849-55-8.mol
NYLIDRIN HYDROCHLORIDE Chemical Properties
- Melting point:
- 198-199℃ (decomposition)
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 41 mg/mL (122.07 mM)
- form
- Solid
- color
- White to Off-White
MSDS
- Language:English Provider:SigmaAldrich
NYLIDRIN HYDROCHLORIDE Usage And Synthesis
Chemical Properties
White, crystals or powder, odorless; tasteless. Slightly soluble in water and alcohol; very slightly soluble in chloroform, ether; pH of 1% solution is between 4.5 and 6.5.
Originator
Buphenine hydrochloride,Troponwerke
Uses
Medicine (treatment of heart disease).
Definition
ChEBI: Nylidrin hydrochloride is an alkylbenzene.
Manufacturing Process
The p-benzoxy-α-bromopropiophenone and 1-phenyl-3-amino-butane were
heating for an hour on the water bath in the absence of solvents. A solid
crystalline cake was obtained. After being extracted with boiling acetic acid,
the hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone-1
was obtained.
The hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone-
1 was suspended in very pure methanol and shaken with a 10% palladium
hydroxide barium sulfate catalyst in contact with, hydrogen. After rather more
than 2 mols of hydrogen had been taken-up the hydrogenation stopped. The
1-(p-hydroxyphenyl)-2-(3-phenylbutylamino)propanol-1, was filtered, washed
with methanol and evaporated, melting point 110-111°C.
Therapeutic Function
Vasodilator
NYLIDRIN HYDROCHLORIDESupplier
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NYLIDRIN HYDROCHLORIDE(849-55-8)Related Product Information
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