ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > Dolutegravir 2-Desfluoro Impurity
Dolutegravir 2-Desfluoro Impurity
Dolutegravir 2-Desfluoro Impurity Basic information
- Product Name:
- Dolutegravir 2-Desfluoro Impurity
- Synonyms:
-
- 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity
- Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- Dolutegravir Impurity G
- Dolutegravir 2-Desfluoro Impurity
- 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
- (4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- Dolutegravir Impurity 47
- Dolutegravir Impurity 50
- CAS:
- 1863916-88-4
- MF:
- C20H20FN3O5
- MW:
- 401.39
- Mol File:
- 1863916-88-4.mol
More
Less
Dolutegravir 2-Desfluoro Impurity Chemical Properties
- Boiling point:
- 675.7±55.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 4.50±1.00(Predicted)
- color
- Off-White to Light Brown
More
Less
Dolutegravir 2-Desfluoro Impurity Usage And Synthesis
Uses
Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir 2-Desfluoro ImpuritySupplier
Shenzhen Roark Pharma-Tec Co., Ltd. Gold
- Tel
- 13128912434
- 2880126944@qq.com
Beijing Comparison Pharmaceutical Technology Co., Ltd
- Tel
- 010-52878169 15701683040
- sales@bjcomparison.com
ChemStrong Scientific Co.,Ltd
- Tel
- 0755-66853366 13670046396
- sales@chem-strong.com
Shanghai CR Corporation Limited
- Tel
- 4006653949
- fred.wen@crcorporation.cn
sgtlifesciences pvt ltd
- Tel
- +8617013299288
- dj@sgtlifesciences.com