Basic information Safety Supplier Related

Lapatinib 2-Fluoro Impurity

Basic information Safety Supplier Related

Lapatinib 2-Fluoro Impurity Basic information

Product Name:
Lapatinib 2-Fluoro Impurity
Synonyms:
  • Lapatinib Impurity 45
  • Lapatinib 2-Fluoro Analog
  • N-(3-chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate)
  • N-[3-Chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine
  • N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
  • 4-Quinazolinamine, N-[3-chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-
CAS:
1393112-45-2
MF:
C29H26ClFN4O4S
MW:
581.06
Mol File:
1393112-45-2.mol
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Lapatinib 2-Fluoro Impurity Chemical Properties

Boiling point:
752.5±60.0 °C(Predicted)
Density 
1.381±0.06 g/cm3(Predicted)
pka
6.34±0.19(Predicted)
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Lapatinib 2-Fluoro Impurity Usage And Synthesis

Uses

3-Desfluoro 2-Fluoro Lapatinib is a compound related to drug Lapatinib (L175808), which is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. Lapatinib is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.

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