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2-Bromo-4-fluorobenzoic acid

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2-Bromo-4-fluorobenzoic acid Basic information

Product Name:
2-Bromo-4-fluorobenzoic acid
Synonyms:
  • RARECHEM AL BO 1996
  • BUTTPARK 18\02-85
  • 2-BROMO-4-FLUOROBENZOIC ACID
  • 2-Bromo-4-Fluorobenzoic
  • 2-Bromo-4-fluorobenzoicacid98%
  • 2-bromo-4-fluorobenzioc acid
  • 2-BroMo-4-fluorobenzoic Acid, 97+%
  • Benzoicacid, 2-bromo-4-fluoro-
CAS:
1006-41-3
MF:
C7H4BrFO2
MW:
219.01
EINECS:
600-118-8
Product Categories:
  • intermediate
  • Benzoic acid series
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Benzoic acid
  • Fluorobenzene
  • Acids & Esters
  • FINE Chemical & INTERMEDIATES
  • Carboxes
  • FluoroCompounds
  • Bromine Compounds
  • Fluorine Compounds
  • C7
  • Carbonyl Compounds
  • Carboxylic Acids
  • Fluorin-contained Benzoic acid series
  • blocks
  • Bromides
Mol File:
1006-41-3.mol
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2-Bromo-4-fluorobenzoic acid Chemical Properties

Melting point:
172-176 °C (lit.)
Boiling point:
294.3±25.0 °C(Predicted)
Density 
1.7218 (rough estimate)
refractive index 
1.4240 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
2.79±0.10(Predicted)
color 
White to Almost white
Water Solubility 
Soluble in water and methanol.
BRN 
2614292
InChIKey
RRKPMLZRLKTDQV-UHFFFAOYSA-N
CAS DataBase Reference
1006-41-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990

MSDS

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2-Bromo-4-fluorobenzoic acid Usage And Synthesis

Chemical Properties

white fine powder

Uses

2-Bromo-4-fluorobenzoic acid is used in the synthesis of 3-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-((2-carboxy-5-fluorophenyl)amino)-3-methoxybenzoic acid and 2-bromo-4-fluorobenzamide. It is also used in the preparation of boron-containing anti-fungal agents, in the treatment of onychomycosis.

General Description

Amination of 2-bromo-4-fluorobenzoic acid with aniline is reported to yield N-phenyl-4-fluoro-anthranilic acid.

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