4,6-Diaminopyrimidine Chemical Properties

Melting point:

270-271°C

Boiling point:

364.0±22.0 °C(Predicted)

Density 

1.368±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to crystal

pka

5.78±0.10(Predicted)

color 

White to Almost white

InChI

InChI=1S/C4H6N4/c5-3-1-4(6)8-2-7-3/h1-2H,(H4,5,6,7,8)

InChIKey

MISVBCMQSJUHMH-UHFFFAOYSA-N

SMILES

C1=NC(N)=CC(N)=N1

CAS DataBase Reference

2434-56-2(CAS DataBase Reference)

Safety Information

HS Code 

29335990

4,6-Diaminopyrimidine Usage And Synthesis

Chemical Properties

Yellow to light yellow crystal

Uses

4,6-Diaminopyrimidine is a compound used for the preparations of pharmaceutical goods. It was shown that organotin polyamines derived from reaction with 4,6-diaminopyrimidines displayed good inhibition of two pancreatic cancer cell lines.

Synthesis

General procedure for the synthesis of 4,6-diaminopyrimidine from the compound (CAS:40070-06-2): 250 mL of 11.5 mol/L hydrochloric acid solution was added to the 4,6-diamino-2-sulfinic acid pyrimidine filter cake obtained in step 2, and the mixture was cooled to -5 °C and stirred continuously for 0.5 h. The mixture was then purified to -5 °C and stirred continuously for 0.5 h. The mixture was purified to -5 °C and stirred continuously for 0.5 h. The mixture was purified to -5 °C and stirred continuously for 0.5 h. The yield of this step was 100%.

References

[1] Patent: CN103709164, 2016, B. Location in patent: Paragraph 0034; 0090; 0105; 0108
[2] Journal of the Chemical Society, 1946, p. 4106,4109
[3] Journal of the Chemical Society, 1946, p. 4106,4109

4,6-Diaminopyrimidine(2434-56-2)Related Product Information

• 4,4'-Methylenedianiline
• Iminodiacetic acid
• Iminodiacetonitrile
• 4-Aminopyrimidine
• 2-Aminopyrimidine
• Diaminomaleonitrile
• 4,6-DIAMINO-2-METHYLMERCAPTOPYRIMIDINE
• 4,6-DIAMINO-5-NITROPYRIMIDINE
• 5,6-Diaminopyrimidine-4(1H)-thione
• 4-CHLORO-2,6-DIAMINOPYRIMIDINE (2,4-DIAMINO-6-CHLOROPYRIMIDINE)
• 5,6-Diamino-1,3-dimethyluracil hydrate
• 2,4,6-Triaminopyrimidine
• 4,5,6-TRIAMINOPYRIMIDINE SULFATE
• 4,5,6-TRIAMINOPYRIMIDINE
• 5-Nitro-2,4,6-triaminopyrimidine
• 4,6-Diaminopyrimidine-2-thiol ,98%,4,6-Diaminopyrimidine-2(1H)-thione
• Pyrimidinetetraamine/sulfuric acid,(1:x)
• 5-Nitroso-2,4,6-triaminopyrimidine