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PONCIRIN

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PONCIRIN Basic information

Product Name:
PONCIRIN
Synonyms:
  • ISOSAKURANETIN-7-NEOHESPERIDOSIDE
  • ISOSAKURANETIN-7-O-NEOHESPERIDOSID
  • ISOSAKURANETIN-7-O-NEOHESPERIDOSIDE
  • PONCIRIN
  • (S)-5,7-DIHYDROXY-4'-METHOXYFLAVANONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]
  • (s)-5,7-dihydroxy-4'-methoxyflavanone-7-[2-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]
  • C09830
  • PONCIRIN WITH HPLC
CAS:
14941-08-3
MF:
C28H34O14
MW:
594.57
EINECS:
239-020-1
Product Categories:
  • Flavanones
Mol File:
14941-08-3.mol
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PONCIRIN Chemical Properties

Melting point:
210°C
Boiling point:
900.1±65.0 °C(Predicted)
Density 
1.59
storage temp. 
Store at -20°C
solubility 
Soluble in methan
pka
7.15±0.40(Predicted)
form 
Solid
color 
Yellow
BRN 
74301
InChIKey
NLAWPKPYBMEWIR-QMIPVYQNSA-N
LogP
3.390 (est)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10
HS Code 
29389090

MSDS

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PONCIRIN Usage And Synthesis

Chemical Properties

Off-white powder

Uses

Poncirin is a natural bitter flavanone glycoside present in many species of citrus fruits which has various biological benefits such as antioxidant, antimicrobial, anti-inflammatory and anti-cancer activities. Main constituent used in traditional Chinese medicine for inflammation, asthma, and infection diseases.

Definition

ChEBI: (2S)-poncirin is a flavanone glycoside that is 4'-methoxy-5,7-dihydroxyflavanone attached to a neohesperidose (alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranose) residue via a glycosidic linkage. It has been isolated from the fruits of Poncirus trifoliata and exhibits inhibitory activity against liopolysaccharide (LPS)-induced prostaglandin E2 and interleukin-6 (IL-6) production. It has a role as a plant metabolite. It is a monomethoxyflavanone, a flavanone glycoside, a disaccharide derivative, a neohesperidoside and a member of 4'-methoxyflavanones. It is functionally related to a 4'-methoxy-5,7-dihydroxyflavanone.

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