BENZO(C)PHENANTHRENE
BENZO(C)PHENANTHRENE Basic information
- Product Name:
- BENZO(C)PHENANTHRENE
- Synonyms:
-
- BENZO(C)PHENANTHRENE
- Benzo[c]phenanthrene (purity)
- 60624, Benzo[c]phenanthrene (purity)
- 3,4-Benzo[c]phenanthrene
- 3,4-Benzo[c]phenthrene
- AR-G 3 BENZO(C)PHENANTHRENE
- 3,4-Benzophenanthrene
- 3,4-Benzphenanthrene
- CAS:
- 195-19-7
- MF:
- C18H12
- MW:
- 228.29
- EINECS:
- 205-896-9
- Product Categories:
-
- Aromatics
- Intermediates & Fine Chemicals
- Alphabetic
- B
- Mutagenesis Research Chemicals
- Pharmaceuticals
- BA - BH
- Mol File:
- 195-19-7.mol
BENZO(C)PHENANTHRENE Chemical Properties
- Melting point:
- 158-160℃
- Boiling point:
- 305.1°C (rough estimate)
- Density
- 1.1209 (estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly)
- color
- Needles from EtOH or pet ether
- BRN
- 1909296
- Stability:
- Light Sensitive
- InChIKey
- TUAHORSUHVUKBD-UHFFFAOYSA-N
- IARC
- 2B (Vol. 92, Sup 7) 2010
- EPA Substance Registry System
- Benzo[c]phenanthrene (195-19-7)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-37/39
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- DI8225000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- mma-sat 25 nmol/plate CNREA8 40,2876,80
BENZO(C)PHENANTHRENE Usage And Synthesis
Chemical Properties
Yellow Solid
Uses
A PAH metabolite having a toxic effect on fish bone metabolite. Also, it is used as a marker of the carcinogenic potency of the polycyclic aromatic hydrocarbons (PAH) mixture. A genotoxic agent.
Definition
ChEBI: An ortho-fused polycyclic arene resulting from the symmetrical fusion of the C1-C2 bonds of two naphthalene units.
Safety Profile
Questionable carcinogen withexperimental tumorigenic data. Mutation data reported.When heated to decomposition it emits acrid and irritatingfumes.
Carcinogenicity
Dermal administration (initiation– promotion protocols) to mice showed benzo[c]phenanthrene was a tumor-initiating agent. Repeated dermal administration in mice or subcutaneous injection into mice or rats gave results considered to be inadequate for evaluation (3). Intraperitoneal injection of benzo[c]phenanthrene into infant mice resulted in a substantial induction of lung tumors. Seven suspected activated metabolites were also active, as well as in two-stage mouse carcinogenesis assays.
Purification Methods
Crystallise benzo[c]phenanthrene from EtOH, pet ether, or EtOH/Me2CO. [Beilstein 5 III 2378, 5 IV 2552.]
BENZO(C)PHENANTHRENESupplier
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BENZO(C)PHENANTHRENE(195-19-7)Related Product Information
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