1-Acetylpyrrolidine Chemical Properties

Boiling point:

105-107°C 15mm

Density 

1.02

refractive index 

1.4700-1.4800

Water Solubility 

Soluble in water

form 

clear liquid

pka

-0.41±0.20(Predicted)

color 

Colorless to Light yellow to Light orange

InChI

InChI=1S/C6H11NO/c1-6(8)7-4-2-3-5-7/h2-5H2,1H3

InChIKey

LNWWQYYLZVZXKS-UHFFFAOYSA-N

SMILES

C(=O)(N1CCCC1)C

CAS DataBase Reference

4030-18-6(CAS DataBase Reference)

Safety Information

Risk Statements 

10

Safety Statements 

16

RIDADR 

1993

HS Code 

2933998090

1-Acetylpyrrolidine Usage And Synthesis

Uses

1-Acetylpyrrolidine is a useful reagent for the synthesis of disubstituted multifunctional indenes.

Synthesis Reference(s)

Tetrahedron, 52, p. 3403, 1996 DOI: 10.1016/0040-4020(96)00037-3
Tetrahedron Letters, 35, p. 477, 1994 DOI: 10.1016/0040-4039(94)85085-2

Research

A rapid method has been developed for determining phenolic hydroxyl groups in lignins. The method comprises acetylation, selective aminolysis of the phenolic acetyl groups by pyrrolidine (aminolysis), and determination of the resulting 1-acetylpyrrolidine by gas chromatography[1].

References

[1] M?nsson, P. “Quantitative Determination of Phenolic and Total Hydroxyl Groups in Lignins.” 1900. 0.

1-Acetylpyrrolidine(4030-18-6)Related Product Information

• 1-ACETYLPYRROLIDINE
• 4-METHOXY-2-METHYLBENZOIC ACID
• 1-ACETYL-2-PYRROLIDONE
• L-Alanyl-L-proline
• (S)-(-)-N-(TRIFLUOROACETYL)PROLYL CHLORIDE
• 1-((PYRROLIDINE-1-CARBONYL)METHYL)PIPERAZINE
• N-CYANOACETYLPYRROLIDINE
• GLYCYL-L-PROLINE
• Actinomycin D
• 1-(4-PIPERIDINYLOXY)ACETYLPYRROLIDINE
• (2S)-1-Acetylpyrrolidine-2α-carboxamide,(S)-1-ACETYLPYRROLIDINE-2-CARBOXAMIDE
• (2S)-1-Acetylpyrrolidine-2α-carboxylic acid
• (2-AMINO-PHENYL)-PYRROLIDIN-1-YL-METHANONE
• N-(2-HYDROXYBENZOYL)PYRROLIDINE 97
• H-SER-PRO-OH
• 4-OXO-4-PYRROLIDIN-1-YL-BUTYRIC ACID
• Z-PHE-PRO-NH2
• PHE-PRO