(S)-2-Amino-2-(2,4-difluorophenyl)ethan-1-ol hydrochloride Chemical Properties

storage temp. 

Inert atmosphere,Room Temperature

Appearance

White to off-white Solid

InChI

InChI=1/C8H9F2NO.ClH/c9-5-1-2-6(7(10)3-5)8(11)4-12;/h1-3,8,12H,4,11H2;1H/t8-;/s3

InChIKey

OWOSOCQHBOENHK-JNODIIHCNA-N

SMILES

[C@@H](C1C=CC(F)=CC=1F)(N)CO.Cl |&1:0,r|

(S)-2-Amino-2-(2,4-difluorophenyl)ethan-1-ol hydrochloride Usage And Synthesis

Uses

Used as an intermediate for organic synthesis.

Preparation

The commonly used method involves the reaction of 2,4-difluorobenzaldehyde with ethylene glycol in the presence of a catalyst, followed by the addition of ammonium chloride and hydrochloric acid to obtain (S)-2-Amino-2-(2,4-difluorophenyl)ethan-1-ol hydrochloride. This method has shown good efficiency and yield, with the advantage of using readily available starting materials.