2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide Chemical Properties

Boiling point:

492.3±45.0 °C(Predicted)

Density 

1.469±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO: soluble

form 

A crystalline solid

pka

9.71±0.43(Predicted)

color 

White to off-white

2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide Usage And Synthesis

Uses

SR 16832 is a dual site PPARγ inhibitor. Acts at orthosteric and allosteric sites in the ligand binding domain. Inhibits binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonists.

Biological Activity

SR16832 is a PPARγ antagonist. It acts as a dual-site covalent inhibitor of PPARγ inhibiting both orthosteric and allosteric cellular activation by the PPARγ agonists.

storage

Store at +4°C

2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide(2088135-12-8)Related Product Information

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