2,4,4'-TRIHYDROXYBENZOPHENONE Chemical Properties

Melting point:

197-198 °C(lit.)

Boiling point:

332.2°C (rough estimate)

Density 

1.2683 (rough estimate)

refractive index 

1.4977 (estimate)

Water Solubility 

Slightly soluble in water

form 

powder to crystal

pka

7.59±0.35(Predicted)

color 

White to Light yellow to Light orange

CAS DataBase Reference

1470-79-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

WGK Germany 

3

HS Code 

2914.50.3000

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

2,4,4'-TRIHYDROXYBENZOPHENONE Usage And Synthesis

Chemical Properties

orange powder or chunks

Uses

2,4,4''-Trihydroxybenzophenone is a small molecule inhibitor of viral replication.

Preparation

Preparation by reaction of 4-hydroxybenzoic acid with resorcinol,
? in the presence of zinc chloride at 160° (Nencki reaction);
? in the presence of zinc chloride and phosphorous oxychloride for 4 days at r.t. (78%);
in the presence of zinc chloride and a mixture of polyphosphoric acid/85% phosphoric acid (60:40) at 27°. Then, during 2 h, phosphorous trichloride was added between 27° and 37° and the mixture heated at 60° for 16 h (quantitative yield);
? in the presence of hydrofluoric acid at 75° in an autoclave.

2,4,4'-TRIHYDROXYBENZOPHENONE(1470-79-7)Related Product Information

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