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Cyclopropylmagnesium bromide

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Cyclopropylmagnesium bromide Basic information

Product Name:
Cyclopropylmagnesium bromide
Synonyms:
  • Cyclopropylmagnesium bromide solution( 1.0 M solution in THF)
  • Cyclopropylmagnesium bromide solution( 0.5 M solution in THF)
  • Bromocyclopropylmagnesium
  • Cyclopropylbromomagnesium
  • Cyclopropylmagnesium bromide, ca 0.5M in THF
  • Cyclopropylmagnesium Bromide (15% in Tetrahydrofuran, ca. 1mol/L)
  • cyclopropylmagnesium bromide solution
  • Cyclopropylmagnesium bromide,0.5M solution inTHF
CAS:
23719-80-4
MF:
C3H5BrMg
MW:
145.28
EINECS:
472-500-0
Product Categories:
  • Grignard Reagent
  • 25mL Sure/Seal Reagents
  • Cyclopropanes
  • Grignard Reagents
  • Chemical Synthesis
  • Organometallic Reagents
  • Grignard Reagents & Alkyl Metals
  • Simple 3-Membered Ring Compounds
  • Synthetic Organic Chemistry
  • Alkyl
  • Grignard Reagents
  • Organometallic Reagents
Mol File:
23719-80-4.mol
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Cyclopropylmagnesium bromide Chemical Properties

Boiling point:
65 °C
Density 
0.968 g/mL at 25 °C
Flash point:
65°C
storage temp. 
2-8°C
form 
Turbid Liquid
color 
Yellow to green
Water Solubility 
Soluble in water (17 mg/ml), (25°C). Soluble in organic solvents.
Sensitive 
Air & Moisture Sensitive
InChIKey
QUPLLJGAJVXXBW-UHFFFAOYSA-M
CAS DataBase Reference
23719-80-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
F,Xi,C
Risk Statements 
11-14-19-36/37/38-40-37-34
Safety Statements 
16-26-45-36/37/39
RIDADR 
UN 3399 4.3/PG 2
WGK Germany 
1
HazardClass 
4.3
PackingGroup 
II
HS Code 
29319090

MSDS

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Cyclopropylmagnesium bromide Usage And Synthesis

Chemical Properties

Clear colorless solution

Uses

It often acts as the starting nutrient mix for dropout studies where fermentation conditions required the absence of one or more essential amino acids. For classifying Yeasts based on colonial characteristics and cell morphology.

Uses

Cyclopropylmagnesium bromide solution has been used in Grignard reaction that finds application as the key step in the preparation of aminopropylindenes, a chemotype of oxidosqualene cyclase (OSC) inhibitors from Grundmann′s ketone. It can react with trimethylborate to form cyclopropylboronic acid, which can undergo Suzuki-type coupling reactions with different aryl, and heteroaryl bromides to form the cyclopropyl adducts.

Uses

Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF)

2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

General Description

This product, 1.0 M in 2-methyltetrahydrofuran aligns with Safer Solvents and Auxiliaries, Use of Renewable Feedstocks and Inherently Safer Chemistry for Accident Prevention.

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