2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE
2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE Basic information
- Product Name:
- 2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE
- Synonyms:
-
- 6-Amino-3-bromo-2,4-iutidine
- 3-Bromo-2,4-dimethylpyridin-6-amine
- 2-AMino-4,6-diMethyl-5-broMopyridine
- 5-BroMo-4,6-diMethylpyridin-2-aMine
- 5-bromo-4,6-dimethyl-2-pyridinamine
- 6-Amino-2,4-dimethyl-3-bromopyridine
- 5-Bromo-4,6-dimethyl-2-pyridinamine, 6-Amino-3-bromo-2,4-lutidine
- 2-AMino-5-broMo-4,6-diMethylpyridine 97%
- CAS:
- 89856-44-0
- MF:
- C7H9BrN2
- MW:
- 201.06
- EINECS:
- 626-748-3
- Product Categories:
-
- Nucleotides
- Amines
- Aromatics
- Bases & Related Reagents
- Heterocycles
- Mol File:
- 89856-44-0.mol
2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE Chemical Properties
- Melting point:
- 144-148 °C (lit.)
- Boiling point:
- 257.7±35.0 °C(Predicted)
- Density
- 1.504±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Chloroform, Methanol
- form
- Off-White to Pale Beige Solid
- pka
- 5.46±0.48(Predicted)
- Appearance
- Off-white to yellow Solid
- InChIKey
- BFRMYMFNSHASRJ-UHFFFAOYSA-N
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-41-43
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- HS Code
- 2933399990
2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE Usage And Synthesis
Chemical Properties
White Powder
Synthesis
5407-87-4
89856-44-0
Example 2: Preparation of 2-amino-5-bromo-4,6-dimethylpyridine (13): 2.00 g (16.32 mmol) of 2-amino-4,6-dimethylpyridine was dissolved in 25 mL of acetonitrile under argon protection and 2.90 g (16.32 mmol) of N-bromosuccinimide was added with stirring. The reaction mixture was stirred at room temperature for 5 hours. Upon completion of the reaction, the resulting precipitate was collected by filtration and dried to afford the target product 2-amino-5-bromo-4,6-dimethylpyridine as a white solid in a yield of 2.76 g (84% yield). The structure of the product was confirmed by 1H-NMR (CDCl3) δ 6.22 (s, 1H), 4.39 (br, 2H), 2.48 (s, 3H), 2.25 (s, 3H) and 13C-NMR (CDCl3) δ 156.34, 155.23, 148.64, 112.26, 108.10, 25.10, 23.30.
References
[1] Organic Process Research and Development, 2012, vol. 16, # 1, p. 109 - 116
[2] Patent: WO2011/103536, 2011, A1. Location in patent: Page/Page column 43-44
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 17, p. 5188 - 5201
[4] Pharmacy and Pharmacology Communications, 1999, vol. 5, # 3, p. 233 - 238
[5] Patent: WO2018/108671, 2018, A1. Location in patent: Page/Page column 178; 179
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2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE(89856-44-0)Related Product Information
- 2-Amino-3,5-dibromo-4,6-dimethylpyridine
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- 6-AMINO-3-BROMO-4-METHYLPYRIDINE-2-CARBOXAMIDE
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- 5-BROMO-4,6-DIMETHYL-2-(4-METHYLPIPERAZINO)NICOTINONITRILE
- 6-AMINO-3-BROMO-4-METHYLPYRIDINE-2-CARBONITRILE
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- 5-BROMO-N,N,4,6-TETRAMETHYLPYRIDIN-2-AMINE
- 2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE&