4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& CAS#: 207233-90-7

4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Basic information

Product Name:

4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&

Synonyms:

4,4''-DIISOTHIOCYANATOSTILBENE-2,2''-DISULPHONIC ACID DISODIUM SALT
4,4μ-Diisothiocyanato-2,2μ-stilbenedisulfonic acid hydrate disodium salt
4,4μ-Diisothiocyanatostilbene-2,2μ-disulfonic acid hydrate disodium salt
DIDS, Disodium 4,4μ-diisothiocyanatostilbene-2,2μ-disulfonate
4,4'-Diisothiocyanatostilbene-2,2'-disulphonic acid disodium salt hydrate
Disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulphonate hydrate
DisodiuM 4,4'-diisothiocyanatostilbene-2,2'-disulfonate, 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodiuM salt hydrate
Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate

CAS:

207233-90-7

MF:

C16H13N2NaO7S4

MW:

496.52

Product Categories:

homoXlink

Mol File:

207233-90-7.mol

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4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Chemical Properties

storage temp.: 2-8°C
solubility: 0.1 M potassium bicarbonate: soluble50mg/mL
form: powder
color: yellow
BRN: 8179433

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Safety Information

Hazard Codes: Xn
Risk Statements: 36/37/38-42
Safety Statements: 22-26
WGK Germany: 3
HS Code: 29309090

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4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Usage And Synthesis

Uses

4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used:

as band3 protein inhibitor in rabbits(19)
for the inhibition of bicarbonate transporters in brain slice tissue(20)
as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)

Biochem/physiol Actions

4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles.

4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&Supplier

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Email: waley188@sohu.com

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com

Henan Alfa Chemical Co., Ltd

Tel: +8618339805032
Email: alfa4@alfachem.cn

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 18108052721
Email: 2850505130@qq.com

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