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QUAZEPAM

Basic information Safety Supplier Related

QUAZEPAM Basic information

Product Name:
QUAZEPAM
Synonyms:
  • Quazepam solution
  • dormalin
  • oniria
  • prosedar
  • quazepam
  • quazium
  • sch16134
  • QUAZEPAM CIV (200 MG)
CAS:
36735-22-5
MF:
C17H11ClF4N2S
MW:
386.79
EINECS:
253-179-4
Mol File:
36735-22-5.mol
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QUAZEPAM Chemical Properties

Melting point:
137.5-139°
Boiling point:
429.9±55.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
0.49±0.20(Predicted)
CAS DataBase Reference
36735-22-5(CAS DataBase Reference)
NIST Chemistry Reference
Quazepam(36735-22-5)
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Safety Information

RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2933996500
Toxicity
LD50 in mice (mg/kg): >1370 i.v., >5000 orally (Orgini); LD50 in male, female mice, rats (mg/kg): 845, 921, 3072, 2749 i.p. (Black)
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QUAZEPAM Usage And Synthesis

Description

Quazepam is a rapidly acting, short term hypnotic reported to exhibit a low incidence of side effects.

Originator

Schering (USA)

Uses

Quazepam is a benzodiazepine derivative drug and is known to bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activty, motor coordination and memory. Quazepam is known to induce motor impairment and exerts hypnotic properties. Quazepam is often used for the treatment of insomina.

Definition

ChEBI: Quazepam is a benzodiazepine.

brand name

Doral (Questcor).

General Description

Quazepam (Doral) and its active metabolitesreportedly are relatively selective for the benzodiazepinemodulatory site on GABAA receptors with α1 subunitand are hypnotic agents. Quazepam is metabolized by oxidation to the 2-oxo compound and then N-dealkylation.Both metabolites are active; the first reportedly is the morepotent and selective. Thereafter, 3-hydroxylation and glucuronidationoccur.

QUAZEPAM Supplier

LGM Pharma
Tel
1-(800)-881-8210
Email
inquiries@lgmpharma.com
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Email
sj_scrc@sinopharm.com
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Email
cdhxsj@163.com
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Email
xg01_gj@163.com
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com