Amikacin sulfate salt
Amikacin sulfate salt Basic information
- Product Name:
- Amikacin sulfate salt
- Synonyms:
-
- AMIKACIN SULFATE 1:1.8
- Amikacin sulfate salt
- (2S)-4-AMino-N-{(1R,2S,3S,4R,5S)-5-aMino-2-[(3-aMino-3-deoxy-a-D-glucopyranosyl)oxy]-4-[(6-aMino-6-deoxy-a-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanaMide sulfate (1:2)
- AMIKASIN SULFATE
- Amikacin sulfate(5:9)
- AMIKACIN SULFATE SALT, AMINOGLYCOSID
- mikacin disulfate salt
- liusuanamukaxonm
- CAS:
- 149022-22-0
- MF:
- C22H45N5O17S
- MW:
- 683.68
- EINECS:
- 254-648-6
- Product Categories:
-
- APIs
- Mol File:
- 149022-22-0.mol
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Amikacin sulfate salt Chemical Properties
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- H2O: soluble50mg/mL
- form
- solid
- color
- white to off-white
- biological source
- synthetic
- InChIKey
- HIBICIOPDUTNRR-BOEHXBESSA-N
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Amikacin sulfate salt Usage And Synthesis
Uses
Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .
General Description
Chemical structure: aminoglycoside
Biochem/physiol Actions
Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.
in vivo
Amikacin (320 mg/kg; subcutaneous injection; daily; for 10 days; male Fischer rats) treatment increases the chance of serious hearing loss in rats in vivo[3].
| Animal Model: | Male Fischer 344 rats (40-50-day-old)[3] |
| Dosage: | 320?mg/kg |
| Administration: | Subcutaneous injection; daily; for 10 days |
| Result: | Induced hearing loss in rats. |
IC 50
Aminoglycoside
Amikacin sulfate saltSupplier
Chengdu Brilliant Pharmaceutical Co., Ltd. Gold
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Shanghai T&W Pharmaceutical Co., Ltd.
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Amikacin sulfate salt(149022-22-0)Related Product Information
- AMIKACIN
- Dimethyl sulfate
- Amikacin Disulfate
- Magnesium sulfate heptahydrate
- Sodium sulfate
- Ammonium sulfate
- Barium sulfate
- Aluminum sulfate
- Agmatine sulfate
- sulfate
- 4-ACETAMIDOCYCLOHEXANOL
- KANAMYCIN ACID SULFATE
- N-(2-HYDROXYETHYL)LACTAMIDE
- KANAMYCIN SULFATE
- KANAMYCIN
- METHYL 6-AMINO-6-DEOXY-GALACTOPYRANOSIDE
- 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine
- (1R,2R)-2-(PROPYLAMINO)CYCLOHEXANOL