7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical Properties

Melting point:

>185°C (dec._)

Boiling point:

517.6±50.0 °C(Predicted)

Density 

1.59±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Aqueous Base (Slightly), DMSO (Very Slightly, Heated)

pka

3.04±0.50(Predicted)

form 

Solid

color 

White to Pale Beige

InChI

InChI=1S/C8H10N2O3S/c1-3-2-14-7-4(9)6(11)10(7)5(3)8(12)13/h4,7H,2,9H2,1H3,(H,12,13)

InChIKey

NVIAYEIXYQCDAN-UHFFFAOYSA-N

SMILES

N12C(C(N)C1=O)SCC(C)=C2C(O)=O

Safety Information

Hazard Codes 

Xn

Risk Statements 

42/43

Safety Statements 

36

7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Usage And Synthesis

Uses

7-Aminodesacetoxycephalosporanic Acid (Cefadroxil EP Impurity B) is a metabolite of Cephalexin (C256800).

Application

7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (7-ADCA) is an important intermediate for oral cephalosporins, and is mainly used in the synthesis of antibiotics such as cephalosporin, cefadroxil, cefradine, and others.

7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(26395-99-3)Related Product Information

• Ethyl 2-(Chlorosulfonyl)acetate
• Acetonitrile
• Methanol
• Kresoxim-methyl
• Basic Violet 1
• Benzocaine
• Folic acid
• Paraquat dichloride
• Acetaminophen
• 4-Aminobenzoic acid
• 7-Aminocephalosporanic acid
• Methylparaben
• Urethane
• Methyl acrylate
• POLYURETHANE
• Cefadroxil EP Impurity C
• Cefadroxil Oxide Impurity
• L-Cefadroxil