Basic information Safety Supplier Related

MMP-9 INHIBITOR I

Basic information Safety Supplier Related

MMP-9 INHIBITOR I Basic information

Product Name:
MMP-9 INHIBITOR I
Synonyms:
  • MMP-9 INHIBITOR I
  • MMP-9 Inhibitor II
  • MMP-9 Inhibitor
  • MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem
  • Benzamide, 5-[(diethylamino)methyl]-N-hydroxy-2-[[(4-methoxyphenoxy)sulfinyl](phenylmethyl)amino]-3-methyl-
CAS:
1177749-58-4
MF:
C27H33N3O5S
MW:
511.63
Mol File:
1177749-58-4.mol
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MMP-9 INHIBITOR I Chemical Properties

Density 
1.276±0.06 g/cm3(Predicted)
storage temp. 
-20C
form 
Off-white solid
pka
8.28±0.42(Predicted)
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MMP-9 INHIBITOR I Usage And Synthesis

Definition

ChEBI: MMP9 inhibitor I is a hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35). It has a role as an EC 3.4.24.35 (gelatinase B) inhibitor. It is a hydroxamic acid, a tertiary amino compound, a sulfonamide and an aromatic ether.

General Description

A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 μM) and MMP-13 IC50 = 113 nM) at higher concentrations.

Biochem/physiol Actions

Primary TargetMMP-9

MMP-9 INHIBITOR ISupplier

Alabiochem Tech.Co., Ltd.
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