N-Acetyl-L-tyrosine Chemical Properties

Melting point:

149-152 °C(lit.)

alpha 

47.5 º (c=2, water)

Boiling point:

364.51°C (rough estimate)

Density 

1.2446 (rough estimate)

refractive index 

1.4960 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

H2O: soluble25mg/mL

form 

Crystalline

pka

3.15±0.10(Predicted)

color 

White to Off-White

Water Solubility 

Soluble in water (25 mg/ml), and ethanol.

BRN 

2697172

Stability:

Stable. Incompatible with strong oxidizing agents.

LogP

1.320

CAS DataBase Reference

537-55-3(CAS DataBase Reference)

NIST Chemistry Reference

N-acetyl-Tyr(537-55-3)

EPA Substance Registry System

N-Acetyl-L-tyrosine (537-55-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

41-36/37/38

Safety Statements 

26-39-36

WGK Germany 

3

F 

10

TSCA 

Yes

HS Code 

29242995

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N-Acetyl-L-tyrosine Usage And Synthesis

Chemical Properties

N-Acetyl-L-Tyrosine is a white crystalline powder that is an acetyl derivative of the amino acid, L-tyrosine. It is freely soluble in water compared to L-tyrosine and is commonly used as a parenteral nutrition supplement. N-Acetyl-L-tyrosine , a stable and more soluble form of tyrosine , has been incorporated in some currently available commercial parenteral amino acid formulations such as TrophAmine and Aminosyn-II.

Uses

N-Acetyl-L-tyrosine is involved in catecholamine production. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Definition

ChEBI: N-acetyl-L-tyrosine is an N-acetyltyrosine in which the chiral centre has L configuration. It has a role as an EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor, a biomarker and a human urinary metabolite. It is a N-acyl-L-tyrosine and a N-acetyltyrosine. It is a conjugate acid of a N-acetyl-L-tyrosinate.

Application

N-Acetyl-L-tyrosine is a tyrosine derivative with a chemical structure similar to that of an amino acid. It is used as a model system in biochemistry and molecular biology to study the transfer reactions of tyrosine, which are important for energy metabolism, protein synthesis, and metal chelation. N-acetyl-L-tyrosine may be used as an indicator to distinguish neurosyphilis patients from syphilis/non-neurosyphilis patients. N-acetyl-L-tyrosine is a precursor of the essential neurotransmitter dopamine.

benefits

N-Acetyl-L-Tyrosine (NALT) plays a necessary part in the synthesis of dopamine and other hormones in your body. It can boost levels of the neurotransmitters dopamine, norepinephrine and epinephrine. It helps to support higher levels of focus and cognitive function. It can increase working memory and feelings of well-being.

Side effects

L-tyrosine gets the generally regarded as safe (GRAS) stamp of approval from the FDA. Some side effects of N-Acetyl-L-tyrosine (NALT) include nausea, headache, fatigue, and heartburn. It can be safely taken for extended periods of time.

N-Acetyl-L-tyrosine(537-55-3)Related Product Information

• H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH
• Acetyl coenzyme A sodium salt
• Boc-D-Tyr-OH
• Acetyl chloride
• Acetylacetone
• L-Tyrosine
• TYROSINASE
• Ethyl 2-(acetylamino)-3-[3,5-diamino-4-(4-methoxyphenoxy)phenyl]propanoate
• Ethyl N-acetyl-L-tyrosinate hydrate
• Ethyl N-benzoyl-L-tyrosinate
• N-ACETYL-L-TYROSINE ETHYL ESTER
• N-Acetyl-3,5-dinitro-L-tyrosine
• N-CBZ-VAL-TYR METHYL ESTER
• N-Glycyl-L-tyrosine
• 3,5-DIIODO-N-ACETYL-L-TYROSINE,3,5-DIIODO-N-ACETYL-L-TYROSINE
• CHLOROACETYL-L-TYROSINE
• AC-TYR-OME H2O
• ACETYL-L-TYROSINE-ETHYLESTER, N-(RG),ACETYL-L-TYROSINE-ETHYLESTER, N-(RG)