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Tobramycin sulfate

Basic information Safety Supplier Related

Tobramycin sulfate Basic information

Product Name:
Tobramycin sulfate
Synonyms:
  • TOBRAMYCIN SULFATE SALT
  • TOBRAMYCIN SULPHATE
  • (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxy-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
  • Dartobcin
  • Dicon
  • Nebcine
  • Tobra gobens
  • Tobramycin sulfate [usan]
CAS:
79645-27-5
MF:
C18H39N5O13S
MW:
565.59
EINECS:
616-717-2
Product Categories:
  • API
  • API's
  • AminoglycosidesAntibiotics
  • Antibacterial
  • Antibiotics
  • Antibiotics A to
  • Antibiotics by Application
  • Antibiotics T-ZAntibiotics
  • Antineoplastic and Immunosuppressive AntibioticsAntibiotics
  • Chemical Structure Class
  • Interferes with Protein SynthesisSpectrum of Activity
  • L - Z
  • Mechanism of Action
Mol File:
79645-27-5.mol
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Tobramycin sulfate Chemical Properties

storage temp. 
2-8°C
form 
Liquid
Water Solubility 
Soluble in water (50 mg/ml).
CAS DataBase Reference
79645-27-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T,Xn
Risk Statements 
61-20/21/22
Safety Statements 
53-22-36/37/39-45-3/7/9
WGK Germany 
3
RTECS 
WK2110000

MSDS

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Tobramycin sulfate Usage And Synthesis

Description

Tobramycin Sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity. Following active transport into the cell, tobramycin binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and fixes the 30 S-50 S ribosomal complex at the start codon (AUG), interfering with the initiation of protein synthesis.

Originator

Nebcin (Lilly).

Uses

Tobramycin Sulfate is an antibiofilm formulations.

Indications

Used in the treatment of septicemia (bloodstream infection), infections of the skin, bone, lower respiratory tract, central nervous system, intra-abdominal and complicated recurrent urinary tract infections.

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