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L-Norleucine

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L-Norleucine Basic information

Product Name:
L-Norleucine
Synonyms:
  • alpha-aminocaproic acid
  • L(+)-Norleucine, 99+% 1GR
  • Norleucine Solution
  • (S)-Norleucine
  • Norleucine, L- (8CI)
  • Glycoleucine
  • Hexanoic acid, 2-amino-, (S)-
  • n-C4H9CH(NH2)COOH
CAS:
327-57-1
MF:
C6H13NO2
MW:
131.17
EINECS:
206-321-4
Product Categories:
  • Amino Acids
  • Amino Acids
  • Leucine [Leu, L]
  • Unusual Amino Acids
  • Amino Acids & Derivatives
  • Isotope Labelled Compounds
Mol File:
327-57-1.mol
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L-Norleucine Chemical Properties

Melting point:
>300 °C (lit.)
alpha 
22 º (c=2, 6N HCl)
Density 
1.1720 (estimate)
refractive index 
23 ° (C=5, 5mol/L HCl)
Flash point:
275 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
1.6 g/100 mL (23°C)
Boiling point:
234.0±23.0 °C(Predicted)
form 
Crystalline Powder
pka
2.335(at 25℃)
color 
White to off-white
PH
6.08
optical activity
+4.725 (H2O) +24.525 (5 mol dm-3 HCl)
Water Solubility 
1.6 g/100 mL (23 ºC)
Sublimation 
275 ºC
Merck 
14,6706
BRN 
1721750
LogP
0.920 (est)
CAS DataBase Reference
327-57-1(CAS DataBase Reference)
NIST Chemistry Reference
L-Norleucine(327-57-1)
EPA Substance Registry System
L-Norleucine (327-57-1)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37-24/25-22
WGK Germany 
3
RTECS 
RC6308000
TSCA 
Yes
HS Code 
29224995

MSDS

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L-Norleucine Usage And Synthesis

Chemical Properties

white to off-white crystalline powder

Uses

A non-essential amino acid. Used as internal standard in amino acid analysis.

Uses

As a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.

Biochem/physiol Actions

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Purification Methods

Crystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]

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