ALLOPURINOL RIBOSIDE
ALLOPURINOL RIBOSIDE Basic information
- Product Name:
- ALLOPURINOL RIBOSIDE
- Synonyms:
-
- 1-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE-4-ONE
- 1-BETA-D-RIBOFURANOSYLPYRAZOLO[3,4-D]PYRIMIDIN-4-ONE
- ALLOPURINOL RIBOSIDE
- 8-AZA-7-DEAZAINOSINE
- 1-β-d-ribofuranosyl-1h-pyrazolo[3,4-d]pyrimidine-4-one
- 1-[(2S,3S,4R,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]-2H-pyrazolo[4,5-e]pyrimidin-4-one
- 1,5-Dihydro-1-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one
- Allopurinol ribonucleoside
- CAS:
- 16220-07-8
- MF:
- C10H12N4O5
- MW:
- 268.23
- Mol File:
- 16220-07-8.mol
More
Less
ALLOPURINOL RIBOSIDE Chemical Properties
- Boiling point:
- 715.0±60.0 °C(Predicted)
- Density
- 2.08±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO:5.0(Max Conc. mg/mL);18.64(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);18.64(Max Conc. mM) - form
- A solid
- pka
- 8.65±0.10(Predicted)
- color
- White to off-white
MSDS
- Language:English Provider:SigmaAldrich
More
Less
ALLOPURINOL RIBOSIDE Usage And Synthesis
Uses
Allopurinol riboside is a structural isomer of hypoxanthine.
Definition
ChEBI: A nucleoside analogue that is allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.
in vivo
Allopurinol riboside peaks in plasma 1.6 hours after administration, has an elimination half-life of 3 hours, and steady-state concentrations in the therapeutic range[3]. After oral administration, unexpectedly low levels of allopurinol riboside in plasma are attributable to incomplete absorption and rapid renal clearance. Probenecid reduces the renal clearance of allopurinol riboside, extends the half-life of allopurinol riboside in plasma, and triples the levels of allopurinol riboside in plasma[4].
IC 50
Leishmania
ALLOPURINOL RIBOSIDESupplier
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Shenzhen Regent Biochemical Technology Co., Ltd.
- Tel
- 0755-85201366 18938635012
- sales@regentsciences.com
Aikon International Limited
- Tel
- 025-58859352 18068836627
- dt3@aikonchem.com
Jinan Yaoyan Pharmaceutical Co., Ltd.
- Tel
- jnyaoyan@163.com
Shenzhen Botel Biotechnology Co. Ltd.
- Tel
- 13316949107 13316968096
- 1979313431@qq.com
More
Less
ALLOPURINOL RIBOSIDE(16220-07-8)Related Product Information
- Allopurinol
- 1-Ethylpyrazole
- 3-Amino-4-pyrazolecarboxamide hemisulfate
- 5-Amino-1-(2-hydroxyethyl)pyrazole
- 5-Amino-1-methylpyrazole-4-carboxamide
- 1-(2-HYDROXYETHYL)-PYRAZOLE
- 1-ETHYL-1H-PYRAZOLE-4-CARBALDEHYDE
- 3-(1H-pyrazol-1-yl)-1-propanol
- 1-Methyl-1H-pyrazole-4-carbaldehyde
- 4-Aminomethyl-1-methylpyrazole
- Pyrimidine
- PYRAZOL-1-YL-METHANOL
- 4-METHYL-2-PROPYL-2 H-PYRAZOL-3-YLAMINE
- CHEMBRDG-BB 4014356
- 2-PROPYL-2H-PYRAZOL-3-YLAMINE
- N-methyl-N-[(1-methyl-1H-pyrazol-4-yl)methyl]amine
- 2-ETHYL-4-METHYL-2H-PYRAZOL-3-YLAMINE
- 5-Amino-1-methyl-1H-pyrazole-4-carbaldehyde