Repirinast Chemical Properties

Melting point:

236-241°

Boiling point:

488.42°C (rough estimate)

Density 

1.2749 (rough estimate)

refractive index 

1.6000 (estimate)

storage temp. 

2-8°C

solubility 

DMSO (Sparingly, Heated), Methanol (Slightly, Heated)

form 

Solid

pka

10.09±0.40(Predicted)

color 

White to Off-White

Water Solubility 

1.2mg/L(temperature not stated)

Safety Information

Toxicity

LD50 in rats, mice (mg/kg): >5000 orally, >5000 s.c. both species (Nagase)

Repirinast Usage And Synthesis

Description

Repirinast is an orally-active antiallergic agent useful in the treatment of allergic asthma. Its activity is reportedly attributed to a metabolite, the corresponding free acid (MY-1250), which is 17 times more potent than disodium cromoglycate in inhibiting histamine release due to antigen-antibody reactions.

Originator

Mitsubishi (Japan)

Uses

Antiallergic.

Definition

ChEBI: Repirinast is an organic molecular entity.

brand name

Romet

Repirinast(73080-51-0)Related Product Information

• Quinoline
• RESMETHRIN
• ETHANE
• Montelukast sodium
• Centchroman
• Montelukast
• Pimecrolimus
• Pemirolast potassium
• Dimethyl fumarate
• Tetrahydropyran
• Tetrahydro-4H-pyran-4-one
• tert-Butyldimethylsilyl chloride
• Dimethyl ether
• Dimethyl sulfoxide
• N,N-Dimethylformamide
• 2,6-Dimethyl-4H-pyran-4-one
• 2-(Methoxymethyl)-N,6-dimethylaniline
• AURORA KA-3316