Basic information Safety Supplier Related

Loratadine EP Impurity E

Basic information Safety Supplier Related

Loratadine EP Impurity E Basic information

Product Name:
Loratadine EP Impurity E
Synonyms:
  • LORATADINE HYDROCHLORIDE
  • 4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-3,6-dihydro-1(2H)-pyridinecarboxylic Acid Ethyl Ester
  • Iso Loratadine
  • Ethyl 4-[(11RS)-8-chloro-6,11-dihydro -5H-benzo[5,6] cyclohepta[1,2-b] pyridin-11-yl]-3,6-dihydropyridine-1(2H)-carboxylate
  • Loratadine EP Impurity E (Iso Loratadine)
  • Loratadine Impurity 5(Loratadine EP Impurity E)
  • ethyl 4-(8-chloro-6,11-dihydro-5H-benzo[1,2]cyclohepta[2,4-b]pyridin-11-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
  • Loratadine Impurity 3/Loratadine EP Impurity E
CAS:
170727-59-0
MF:
C22H23ClN2O2
MW:
382.88
EINECS:
607-884-2
Product Categories:
  • Amines
  • Heterocycles
  • Impurity
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
170727-59-0.mol
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Loratadine EP Impurity E Chemical Properties

Melting point:
>50°C (dec.)
Boiling point:
512.6±50.0 °C(Predicted)
Density 
1.253±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Sparingly), Methanol (Slightly)
pka
5.09±0.40(Predicted)
form 
Solid
color 
Off-White to Light Red
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Loratadine EP Impurity E Usage And Synthesis

Chemical Properties

Low Melting Pink Solid

Uses

Iso Loratadine (Loratadine EP Impurity E) is a Loratadine (L469575) impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.

Uses

Loratadine (L469575) impurity, Loratadine EP Impurity E can be used as an isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.

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