Loratadine EP Impurity E Chemical Properties

Melting point:

>50°C (dec.)

Boiling point:

512.6±50.0 °C(Predicted)

Density 

1.253±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

Chloroform (Sparingly), Methanol (Slightly)

pka

5.09±0.40(Predicted)

form 

Solid

color 

Off-White to Light Red

InChI

InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-9,11,14,20H,2,5-6,10,12-13H2,1H3

InChIKey

ZORGYPXITGWTSB-UHFFFAOYSA-N

SMILES

C1N(C(OCC)=O)CC=C(C2C3=NC=CC=C3CCC3=CC(Cl)=CC=C32)C1

Loratadine EP Impurity E Usage And Synthesis

Chemical Properties

Low Melting Pink Solid

Uses

Iso Loratadine (Loratadine EP Impurity E) is a Loratadine (L469575) impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.

Uses

Loratadine (L469575) impurity, Loratadine EP Impurity E can be used as an isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.

Loratadine EP Impurity E(170727-59-0)Related Product Information

• Loratadine
• Desloratadine N-Hydroxypiperidine
• N-ForMyl Desloratadine
• 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester
• Loratadine 2-Chloro IMpurity
• 8-Dechloro-10-chloro Loratadine
• 8-Dechloro-7-chloro Loratadine
• Loratadine
• N-Methyl Desloratadine
• Loratadine Impurity 17
• 3-Hydroxy loratadine
• 4-chloro-loratadine
• 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
• N-Carbethoxy-4-piperidone
• Loratadine EP IMpurity A
• Desloratadine
• Loratadine Impurity 13
• Loratadine Impurity 13