(S)-AMPA Chemical Properties

alpha 

D28 -21 ±2° (c = 0.19 in water)

Density 

1.386±0.06 g/cm3(Predicted)

storage temp. 

Store at RT

form 

White to off-white powder.

pka

2.15±0.10(Predicted)

color 

White

Water Solubility 

Soluble to 100 mM in water

CAS DataBase Reference

83643-88-3(CAS DataBase Reference)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

(S)-AMPA Usage And Synthesis

Uses

Active enantiomer of AMPA that induces apoptosis in cortical neurons

Uses

(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.

Uses

(S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.

General Description

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).

Biological Activity

Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ .

Biochem/physiol Actions

Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.

storage

Room temperature

(S)-AMPA(83643-88-3)Related Product Information

• AMPA
• (RS)-AMPA HYDROBROMIDE,AMPA HYDROBROMIDE,AMPA,(+/-)-AMPA HYDROBROMIDE
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• AMPA,AMPA HYDRATE,(RS)-AMPA
• Anti-Glutamate Receptor AMPA R1 (GluR1) antibody produced in rabbit
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