Basic information Safety Supplier Related

20-BETA-DIHYDROCORTISOL

Basic information Safety Supplier Related

20-BETA-DIHYDROCORTISOL Basic information

Product Name:
20-BETA-DIHYDROCORTISOL
Synonyms:
  • 4-PREGNEN-11-BETA, 17,20-BETA, 21-TETROL-3-ONE
  • 4-PREGNEN-11BETA,17ALPHA,20BETA,21-TETROL-3-ONE
  • 20-BETA-DIHYDROCORTISOL
  • 11β,17α,20β,21-Tetrahydroxy-4-pregnen-3-one
  • 20β-Dihydrocortisol
  • REICHSTEIN'S COMPOUND ''E''
  • REICHSTEIN'S SUBSTANCE 'E'
  • 11-beta,17-alpha-20-beta,21-tetrahydroxypregn-4-en-3-one
CAS:
116-58-5
MF:
C21H32O5
MW:
364.48
Mol File:
116-58-5.mol
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20-BETA-DIHYDROCORTISOL Chemical Properties

Melting point:
125°C (rough estimate)
Boiling point:
415.66°C (rough estimate)
Density 
1.0666 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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20-BETA-DIHYDROCORTISOL Usage And Synthesis

Uses

20β-Dihydrocortisol could be used as a potential non invasive diagnostic test of transmissible spongiform encephalopaties. 20β-Dihydrocortisol is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

Definition

ChEBI: 20beta-dihydrocortisol is a 17alpha-hydroxy-C21-steroid that is cortisol in which the 20-oxo group has been reduced to a hydroxy group. It is a metabolite of cortisol identified in the urine of horses and humans, and its urinary excretion is increased in obesity. It has a role as a human urinary metabolite and a mammalian metabolite. It is a 21-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 20-hydroxy steroid, an 11beta-hydroxy steroid and a 17alpha-hydroxy-C21-steroid. It is functionally related to a cortisol.

20-BETA-DIHYDROCORTISOLSupplier

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